Getting PrEP to the people: opportunities, challenges, and emerging models of PrEP implementation

Details

• Alternative Title:
  Sex Health
• Personal Author:
  Sullivan, Patrick S ; Siegler, Aaron J
• Description:
  Background/Purpose:
  
  Pre-exposure prophylaxis with TDF/FTC is now accepted as an efficacious approach to preventing HIV acquisition among people at high risk for HIV infection, but in most places, PrEP uptake to date has not been sufficient to make large impacts on HIV incidence.
  
  Approach:
  
  Here we consider several key elements of the effort to expand PrEP uptake for at-risk populations who would benefit most: Increasing access to PrEP, integrating PrEP programs with other services, promoting PrEP persistence, and developing systems for monitoring PrEP use.
  
  Outcomes/Impact:
  
  Access to PrEP includes regulatory issues and geographic proximity to PrEP providers. Integrating PrEP programs with other comprehensive sexual health services, through clinic-based programs or through technology-based approaches, offers opportunities to identify PrEP candidates and improve linkages to PrEP care. Once at-risk people are prescribed PrEP, lowering barriers to persistence on PrEP is critical to realizing the most population benefits. To understand progress and identify under-served groups and communities, systems to monitor the uptake of PrEP are needed.
  
  Significance/Innovation:
  
  We argue that making the most of a new biomedical intervention tool requires ongoing research about implementation, scaleup through multiple channels, including community-based organizations, and high-quality monitoring of uptake. We must turn to questions of PrEP implementation and continue to seek innovative approaches to reduce barriers to PrEP uptake and persistence on PrEP.
  
  
• Subjects:
  Administration, Oral Anti-HIV Agents Emtricitabine Health Equity Health Services Accessibility HIV Infections Humans Pre-Exposure Prophylaxis Tenofovir
• Source:
  Sex Health. 15(6):522-527
• Pubmed ID:
  30476461
• Pubmed Central ID:
  PMC6506265
• Document Type:
  Journal Article
• Funding:
  P30 AI050409/AI/NIAID NIH HHSUnited States/ ; U19 HD089881/HD/NICHD NIH HHSUnited States/ ; R01 DA038196/DA/NIDA NIH HHSUnited States/ ; R01 MH114692/MH/NIMH NIH HHSUnited States/ ; U01 PS004977/PS/NCHHSTP CDC HHSUnited States/
• Volume:
  15
• Issue:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:fbe5fe895745cb4f3e8d3cd35b14940b41f039e0ad2df29697ac9f6e941c38e881423828c7f71089c5984ebadaa284d26409843616e8906b709c17e6d7612773
• Download URL:
  https://stacks.cdc.gov/view/cdc/164649/cdc_164649_DS1.pdf
• File Type:
  [PDF - 59.83 KB ]