Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Parola, Philippe ; de Lamballerie, Xavier ; Jourdan, Jacques ; Rovery, Clarisse ; Vaillant, Véronique ; ... More +
Parola, Philippe ; de Lamballerie, Xavier ; Jourdan, Jacques ; Rovery, Clarisse ; Vaillant, Véronique ; Minodier, Philippe ; Brouqui, Philippe ; Flahault, Antoine ; Raoult, Didier ; Charrel, Rémi N. Less -
Description:
Chikungunya virus (CHIKV) emerged in Indian Ocean islands in 2005 and is causing an ongoing outbreak that involves >260,000 patients, including travelers returning home from these islands. We investigated cases in 4 patients returning from Mayotte and Reunion Islands with CHIKV infection and a nurse infected in metropolitan France after direct contact with the blood of a traveler. Four patients had tenosynovitis and pain at wrist pressure, and 1 had life-threatening manifestations. Four CHIKV strains were isolated, including 1 from the patient with the autochthonous case. The complete genomic sequence identified a new CHIKV variant emerging from the East/ central African evolutionary lineage. Aedes albopictus, the implicated vector of CHIKV in Indian Ocean islands, has dispersed worldwide in recent decades. High viral loads in patients returning from Indian Ocean islands to countries where Ae. albopictus is prevalent may be a source of epidemics.
Subjects:
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Adult Aedes Aged Alphavirus Infections Animals Base Sequence Chikungunya Virus Disease Outbreaks Female Humans Infant Insect Vectors Male Middle Aged Molecular Sequence Data Phylogeny Research Reverse Transcriptase Polymerase Chain Reaction Travel
Source:
Emerg Infect Dis. 12(10):1493-1499.
Document Type:
Journal Article
Place as Subject:
Indian Ocean Islands
Location:
Oceania
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:60cee7cb7e304a0c9c82883a64cdd7c1b9fe73e17bdca4489b8829928cc79dda
Download URL:
https://stacks.cdc.gov/view/cdc/16381/cdc_16381_DS1.pdf
File Type:

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