Clusters of Hantavirus Infection, Southern Argentina

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Lázaro, Maria E. ; Cantoni, Gustavo E. ; Calanni, Liliana M. ; Resa, Amanda J. ; Herrero, Eduardo R. ; Iacono, Marisa A. ; Enria, Delia A. ; Cappa, Stella M. González
• Description:
  Person-to-person transmission of a hantavirus was first confirmed during a 1996 outbreak of hantavirus pulmonary syndrome in southern Argentina, where Andes virus is endemic. To identify other episodes of secondary transmission, we reviewed reports of 51 cases of hantavirus infection from this region (November 1993-June 2005). Nine clusters involving 20 cases (39.2%) were found. Two patients, who had symptoms 3 weeks after they shared risks for rodent exposure, were considered a cluster. The other 8 clusters each began with an index case, which was almost always fatal, followed 19-40 days later by the illness of at least 1 person who had close and prolonged contact with the index case-patient. Person-to-person transmission was considered the probable source of these 8 clusters. The probability of initiating secondary cases was 41% for patients who died versus 4% for those who survived (p = 0.005). Interpersonal transmission of Andes virus infection should be considered even when rodent exposure cannot be definitively excluded.
• Subjects:
  Acute Respiratory Distress Syndrome, Research Adolescent Adult Argentina Child Child, Preschool Cluster, Interhuman Transmission, Hantavirus Pulmonary Syndrome, Transmission Cluster Analysis Epidemiology Female Hantavirus, Andes Virus Hantavirus Infections Humans Infant Male Middle Aged Outbreak Research

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• Source:
  Emerg Infect Dis. 13(1):104-110.
• Document Type:
  Journal Article
• Volume:
  13
• Issue:
  1
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3c3f9ed2d7151bd51dbb1d8c4b0e49025e6a085fbe06b290df9751b4ac8cc248
• Download URL:
  https://stacks.cdc.gov/view/cdc/16312/cdc_16312_DS1.pdf
• File Type:
  [PDF - 274.98 KB ]