Lymph Node Biopsy Specimens and Diagnosis of Cat-scratch Disease

Rolain, Jean-Marc; Lepidi, Hubert; Zanaret, Michel; Triglia, Jean-Michel; Michel, Gérard; Thomas, Pascal-Alexandre; Texereau, Michèle; Stein, Andreas; Romaru, Anette; Eb, François; Raoult, Didier

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Lymph Node Biopsy Specimens and Diagnosis of Cat-scratch Disease

Published Date:

Sep 2006

Source:

Emerg Infect Dis. 12(9):1338-1344.

[PDF-126.34 KB]

Details:

Personal Authors:

Rolain, Jean-Marc ; Lepidi, Hubert ; Zanaret, Michel ; Triglia, Jean-Michel ; Michel, Gérard ; ... More ▼

Keywords:

[+]

Description:

We report microbiologic analysis of 786 lymph node biopsy specimens from patients with suspected cat-scratch disease (CSD). The specimens were examined by standard, cell culture, and molecular methods. Infectious agents were found in samples from 391 (49.7%) of 786 patients. The most commonly identified infectious agent was Bartonella henselae (245 patients, 31.2%), the agent of CSD. Mycobacteriosis was diagnosed in 54 patients (6.9%) by culture and retrospectively confirmed by using a specific real-time PCR assay. Neoplasm was diagnosed in 181 specimens suitable for histologic analysis (26.0%) from 47 patients. Moreover, 13 patients with confirmed Bartonella infections had concurrent mycobacteriosis (10 cases) or neoplasm (3 cases). A diagnosis of CSD does not eliminate a diagnosis of mycobacteriosis or neoplasm. Histologic analysis of lymph node biopsy specimens should be routinely performed because some patients might have a concurrent malignant disease or mycobacteriosis.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

	06-0122-F1.gif	image/gif
	06-0122-F1.jpg	image/jpeg
	06-0122-F2.gif	image/gif
	06-0122-F2.jpg	image/jpeg
	06-0122.nxml	text/plain
	license.txt	text/plain

No Related Documents.

You May Also Like:

Bartonella henselae in Skin Biopsy Specimens of Patients with Cat-Scratch Disease

Personal Author:

Angelakis, Emmanouil; Edouard, Sophie; La Scola, Bernard; Raoult, Didier;

Published:

Dec 2010

Source:

Emerg Infect Dis. 16(12):1963-1965.

Description:

During the past 2 years, we identified live Bartonella henselae in the primary inoculation sites of 3 patients after a cat scratch. Although our data are preliminary, we report that a cutaneous swab of the skin lesion from a patient in the early stag...

File Type:

[PDF - 241.94 KB]
Seasonality of Cat-Scratch Disease, France, 1999–2009

Personal Author:

Sanguinetti-Morelli, Diane; Angelakis, Emmanouil; Richet, Hervé; Davoust, Bernard; Rolain, Jean Marc; Raoult, Didier;

Published:

Apr 2011

Source:

Emerg Infect Dis. 17(4):705-707.

Description:

Cat-scratch disease is seasonal in the United States and Japan; but no data are available from Europe. To assess the seasonality of the disease in France, we analyzed lymph node biopsy specimens collected during 1999-2009. Most (87.5%) cases occurred...

File Type:

[PDF - 173.92 KB]
Genetic Diversity of Bartonella henselae in Human Infection Detected with Multispacer Typing

Personal Author:

Li, Wenjun; Raoult, Didier; Fournier, Pierre-Edouard;

Published:

Aug 2007

Source:

Emerg Infect Dis. 13(8):1178-1183.

Description:

We applied multispacer typing (MST) by incorporating 9 variable intergenic spacers to Bartonella henselae DNA detected in lymph node biopsy specimens from 70 patients with cat-scratch disease (CSD), in cardiac valve specimens from 2 patients with end...

File Type:

[PDF - 186.74 KB]
Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes.

Personal Author:

Regnery, R.; Tappero, J.;

Published:

1995 Jan-Mar

Source:

Emerg Infect Dis. 1(1):16-21.

Description:

The search for the infectious agents responsible for cat-scratch disease, bacillary angiomatosis, and related syndromes has a long and often circuitous history. Recognition of the etiologic agents and a new understanding of the fundamental features o...

File Type:

[PDF - 64.22 KB]
Human Case of Bartonella alsatica Lymphadenitis

Personal Author:

Angelakis, Emmanouil; Lepidi, Hubert; Canel, Atbir; Rispal, Patrick; Perraudeau, Françoise; Barre, Isabelle; Rolain, Jean-Marc; Raoult, Didier;

Published:

Dec 2008

Source:

Emerg Infect Dis. 14(12):1951-1953

File Type:

[PDF - 155.99 KB]