Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Courvalin, Patrice
Description:
Evolution of bacteria towards resistance to antimicrobial drugs, including multidrug resistance, is unavoidable because it represents a particular aspect of the general evolution of bacteria that is unstoppable. Therefore, the only means of dealing with this situation is to delay the emergence and subsequent dissemination of resistant bacteria or resistance genes. Resistance to antimicrobial drugs in bacteria can result from mutations in housekeeping structural or regulatory genes. Alternatively, resistance can result from the horizontal acquisition of foreign genetic information. The 2 phenomena are not mutually exclusive and can be associated in the emergence and more efficient spread of resistance. This review discusses the predictable future of the relationship between antimicrobial drugs and bacteria.
Subject:
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Anti-Bacterial Agents
Antibiotics
Antimicrobial Drugs
Bacteria
Bacterial Proteins
Drug Resistance, Bacterial
Evolution
Forecasting
Gene Transfer, Horizontal
Humans
Microbial Sensitivity Tests
Mutation
Perspective
Resistance

Source:
Emerg Infect Dis. 11(10):1503-1506.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:bdaee817c5813999e6394a7b1e259838e3dcf7bbe92ef4d0b7b799c5cc93fb1f
File Type:

Supporting Files

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