Bat-transmitted Human Rabies Outbreaks, Brazilian Amazon

da Rosa, Elizabeth S.T.; Kotait, Ivanete; Barbosa, Taciana F.S.; Carrieri, Maria L.; Brandão, Paulo E.; Pinheiro, Amiraldo S.; Begot, Alberto L.; Wada, Marcelo Y.; de Oliveira, Rosely C.; Grisard, Edmundo C.; Ferreira, Márcia; Lima, Reynaldo J. da Silva; Montebello, Lúcia; Medeiros, Daniele B.A.; Sousa, Rita C.M.; Bensabath, Gilberta; Carmo, Eduardo H.; Vasconcelos, Pedro F.C.

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Bat-transmitted Human Rabies Outbreaks, Brazilian Amazon

Supporting Files Public Domain

Aug 2006
By da Rosa, Elizabeth S.T. ; Kotait, Ivanete ; Barbosa, Taciana F.S.

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

da Rosa, Elizabeth S.T. ; Kotait, Ivanete ; Barbosa, Taciana F.S. ; Carrieri, Maria L. ; Brandão, Paulo E. ; Pinheiro, Amiraldo S. ; Begot, Alberto L. ; Wada, Marcelo Y. ; de Oliveira, Rosely C. ; Grisard, Edmundo C. ; Ferreira, Márcia ; Lima, Reynaldo J. da Silva ; Montebello, Lúcia ; Medeiros, Daniele B.A. ; Sousa, Rita C.M. ; Bensabath, Gilberta ; Carmo, Eduardo H. ; Vasconcelos, Pedro F.C.
Description:

We describe 2 bat-transmitted outbreaks in remote, rural areas of Portel and Viseu Municipalities, Pará State, northern Brazil. Central nervous system specimens were taken after patients' deaths and underwent immunofluorescent assay and histopathologic examination for rabies antigens; also, specimens were injected intracerebrally into suckling mice in an attempt to isolate the virus. Strains obtained were antigenically and genetically characterized. Twenty-one persons died due to paralytic rabies in the 2 municipalities. Ten rabies virus strains were isolated from human specimens; 2 other cases were diagnosed by histopathologic examination. Isolates were antigenically characterized as Desmodus rotundus variant 3 (AgV3). DNA sequencing of 6 strains showed that they were genetically close to D. rotundus-related strains isolated in Brazil. The genetic results were similar to those obtained by using monoclonal antibodies and support the conclusion that the isolates studied belong to the same rabies cycle, the virus variants found in the vampire bat D. rotundus.
Subjects:
Source:

Emerg Infect Dis. 12(8):1197-1202.
Document Type:

Journal Article
Place as Subject:

Brazil
Volume:

12
Issue:

8
Download URL:

https://stacks.cdc.gov/view/cdc/16027/cdc_16027_DS1.pdf
File Type:

[PDF - 289.50 KB]
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:1750f0df41b75e74b19e3b5cea163a70a46cce24393fa70826242485eceab192

File Language:

English

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