Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
da Rosa, Elizabeth S.T. ; Kotait, Ivanete ; Barbosa, Taciana F.S. ; Carrieri, Maria L. ; Brandão, Paulo E. ; ... More +
da Rosa, Elizabeth S.T. ; Kotait, Ivanete ; Barbosa, Taciana F.S. ; Carrieri, Maria L. ; Brandão, Paulo E. ; Pinheiro, Amiraldo S. ; Begot, Alberto L. ; Wada, Marcelo Y. ; de Oliveira, Rosely C. ; Grisard, Edmundo C. ; Ferreira, Márcia ; Lima, Reynaldo J. da Silva ; Montebello, Lúcia ; Medeiros, Daniele B.A. ; Sousa, Rita C.M. ; Bensabath, Gilberta ; Carmo, Eduardo H. ; Vasconcelos, Pedro F.C. Less -
Description:
We describe 2 bat-transmitted outbreaks in remote, rural areas of Portel and Viseu Municipalities, Pará State, northern Brazil. Central nervous system specimens were taken after patients' deaths and underwent immunofluorescent assay and histopathologic examination for rabies antigens; also, specimens were injected intracerebrally into suckling mice in an attempt to isolate the virus. Strains obtained were antigenically and genetically characterized. Twenty-one persons died due to paralytic rabies in the 2 municipalities. Ten rabies virus strains were isolated from human specimens; 2 other cases were diagnosed by histopathologic examination. Isolates were antigenically characterized as Desmodus rotundus variant 3 (AgV3). DNA sequencing of 6 strains showed that they were genetically close to D. rotundus-related strains isolated in Brazil. The genetic results were similar to those obtained by using monoclonal antibodies and support the conclusion that the isolates studied belong to the same rabies cycle, the virus variants found in the vampire bat D. rotundus.
Subject:
[+]
Adolescent Adult Animals Child Child, Preschool Chiroptera Disease Outbreaks Female Humans Male Mice Middle Aged Molecular Sequence Data Rabies Rabies Virus Research Sequence Analysis, DNA
Source:
Emerg Infect Dis. 12(8):1197-1202.
Document Type:
Journal Article
Place as Subject:
Brazil
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:1750f0df41b75e74b19e3b5cea163a70a46cce24393fa70826242485eceab192
Download URL:
https://stacks.cdc.gov/view/cdc/16027/cdc_16027_DS1.pdf
File Type:

Supporting Files

• 	license.txt	txt
  	05-0929-F1.gif	gif
  	05-0929-F1.jpg	jpeg
  	05-0929-F2.gif	gif
  	05-0929-F2.jpg	jpeg
  	05-0929-F3.gif	gif
  	05-0929-F3.jpg	jpeg
  	05-0929.nxml	txt

More +