Rickettsial Infections and Fever, Vientiane, Laos

Phongmany, Simaly; Rolain, Jean-Marc; Phetsouvanh, Rattanaphone; Blacksell, Stuart D.; Soukkhaseum, Vimone; Rasachack, Bouachanh; Phiasakha, Khamphong; Soukkhaseum, Surn; Frichithavong, Khamthavi; Chu, Vang; Keolouangkhot, Valy; Martinez-Aussel, Bertrand; Chang, Ko; Darasavath, Chirapha; Rattanavong, Oudayvone; Sisouphone, Siho; Mayxay, Mayfong; Vidamaly, Sisouphane; Parola, Philippe; Thammavong, Chanpheng; Heuangvongsy, Mayboun; Syhavong, Bounkong; Raoult, Didier; White, Nicholas J.; Newton, Paul N.

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Rickettsial Infections and Fever, Vientiane, Laos

Feb 2006
By Phongmany, Simaly ; Rolain, Jean-Marc ; Phetsouvanh, Rattanaphone ; ...
Source: Emerg Infect Dis. 12(2):256-262.

[PDF-156.36 KB]

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Phongmany, Simaly ; Rolain, Jean-Marc ; Phetsouvanh, Rattanaphone ; Blacksell, Stuart D. ; Soukkhaseum, Vimone ; ... More +

Phongmany, Simaly ; Rolain, Jean-Marc ; Phetsouvanh, Rattanaphone ; Blacksell, Stuart D. ; Soukkhaseum, Vimone ; Rasachack, Bouachanh ; Phiasakha, Khamphong ; Soukkhaseum, Surn ; Frichithavong, Khamthavi ; Chu, Vang ; Keolouangkhot, Valy ; Martinez-Aussel, Bertrand ; Chang, Ko ; Darasavath, Chirapha ; Rattanavong, Oudayvone ; Sisouphone, Siho ; Mayxay, Mayfong ; Vidamaly, Sisouphane ; Parola, Philippe ; Thammavong, Chanpheng ; Heuangvongsy, Mayboun ; Syhavong, Bounkong ; Raoult, Didier ; White, Nicholas J. ; Newton, Paul N. Less -
Description:

Rickettsial diseases have not been described previously from Laos, but in a prospective study, acute rickettsial infection was identified as the cause of fever in 115 (27%) of 427 adults with negative blood cultures admitted to Mahosot Hospital in Vientiane, Laos. The organisms identified by serologic analysis were Orientia tsutsugamushi (14.8%), Rickettsia typhi (9.6%), and spotted fever group rickettsia (2.6% [8 R. helvetica, 1 R. felis, 1 R. conorii subsp. indica, and 1 Rickettsia "AT1"]). Patients with murine typhus had a lower frequency of peripheral lymphadenopathy than those with scrub typhus (3% vs. 46%, p<0.001). Rickettsioses are an underrecognized cause of undifferentiated febrile illnesses among adults in Laos. This finding has implications for the local empiric treatment of fever.
Subjects:

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Adolescent Adult Aged Antibodies, Bacterial Female Fever Humans Immunoglobulin G Immunoglobulin M Laos Male Middle Aged Orientia Tsutsugamushi Prospective Studies Research Rickettsia AT1 Rickettsia Conorii Rickettsia Felis Rickettsia Helvetica Rickettsia Typhi Scrub Typhus Typhus Typhus, Endemic Flea-Borne
Source:

Emerg Infect Dis. 12(2):256-262.
Document Type:

Journal Article
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:cebdf45776108a2391056e6f4ca100d42bbe716cb3a1966df0a4f0387fcbd9b8
Download URL:

https://stacks.cdc.gov/view/cdc/16020/cdc_16020_DS1.pdf
File Type:

	05-0900.nxml	txt
	license.txt	txt

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