Mallards and Highly Pathogenic Avian Influenza Ancestral Viruses, Northern Europe

Munster, Vincent J.; Wallensten, Anders; Baas, Chantal; Rimmelzwaan, Guus F.; Schutten, Martin; Olsen, Björn; Osterhaus, Albert D.M.E.; Fouchier, Ron A.M.

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Mallards and Highly Pathogenic Avian Influenza Ancestral Viruses, Northern Europe

Supporting Files Public Domain

Oct 2005
By Munster, Vincent J. ; Wallensten, Anders ; Baas, Chantal ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Munster, Vincent J. ; Wallensten, Anders ; Baas, Chantal ; Rimmelzwaan, Guus F. ; Schutten, Martin ; Olsen, Björn ; Osterhaus, Albert D.M.E. ; Fouchier, Ron A.M.
Description:

Outbreaks of highly pathogenic avian influenza (HPAI), which originate in poultry upon transmission of low pathogenic viruses from wild birds, have occurred relatively frequently in the last decade. During our ongoing surveillance studies in wild birds, we isolated several influenza A viruses of hemagglutinin subtype H5 and H7 that contain various neuraminidase subtypes. For each of the recorded H5 and H7 HPAI outbreaks in Europe since 1997, our collection contained closely related virus isolates recovered from wild birds, as determined by sequencing and phylogenetic analyses of the hemagglutinin gene and antigenic characterization of the hemagglutinin glycoprotein. The minor genetic and antigenic diversity between the viruses recovered from wild birds and those causing HPAI outbreaks indicates that influenza A virus surveillance studies in wild birds can help generate prototypic vaccine candidates and design and evaluate diagnostic tests, before outbreaks occur in animals and humans.
Subjects:

Animals Animals, Wild Disease Outbreaks Ducks Hemagglutination Inhibition Tests Hemagglutinin Glycoproteins, Influenza Virus Influenza A Virus Influenza A Virus, H5N2 Subtype Influenza A Virus, H7N7 Subtype Influenza In Birds Male Molecular Sequence Data Neuraminidase Phylogeny Sequence Analysis, Dna
Source:

Emerg Infect Dis. 11(10):1545-1551.
Document Type:

Journal Article
Place as Subject:

Europe
Volume:

11
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:abfcf12629730330fb174be24e1d46948ee926f249c4fcbe75a9ef1e23f9c09c
Download URL:

https://stacks.cdc.gov/view/cdc/15926/cdc_15926_DS1.pdf
File Type:

[PDF - 263.92 KB ]

File Language:

English

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