Rifampin-resistant Meningococcal Disease

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Rainbow, Jean ; Cebelinski, Elizabeth ; Bartkus, Joanne ; Glennen, Anita ; Boxrud, Dave ; Lynfield, Ruth
• Description:
  Rifampin-resistant meningococcal disease occurred in a child who had completed rifampin chemoprophylaxis for exposure to a sibling with meningococcemia. Susceptibility testing of 331 case isolates found only 1 other case of rifampin-resistant disease in Minnesota, USA, during 11 years of statewide surveillance. Point mutations in the RNA polymerase Beta subunit (rpoB) gene were found in isolates from each rifampin-resistant case-patient.
• Subjects:
  Anti-Bacterial Agents Bacteremia Child Dispatch DNA-Directed RNA Polymerases Drug Resistance, Bacterial Female Humans Infant Male Meningococcal Infections Microbial Sensitivity Tests Point Mutation Population Surveillance Rifampin

  More +
• Source:
  Emerg Infect Dis. 11(6):977-979.
• Document Type:
  Journal Article
• Funding:
  U50/CCU511190-09/CC/ODCDC CDC HHS/United States
• Place as Subject:
  Minnesota
• Location:
  North America
• Volume:
  11
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:fe208d30ffe9428b66e8a6e2481390d908152e3850e11a64d5919b80aaa4f2ea
• Download URL:
  https://stacks.cdc.gov/view/cdc/15840/cdc_15840_DS1.pdf
• File Type:
  [PDF - 70.20 KB ]