Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Sjölund, Maria ; Tano, Eva ; Blaser, Martin J. ; Andersson, Dan I. ; Engstrand, Lars
Sjölund, Maria ; Tano, Eva ; Blaser, Martin J. ; Andersson, Dan I. ; Engstrand, Lars Less -
Description:
We examined how a common therapy that includes clarithromycin affects normally colonizing Staphylococcus epidermidis. Samples from the nostrils of 5 patients receiving therapy were collected before, immediately after, 1 year after, and 4 years after treatment. From each patient and sample, S. epidermidis strains were isolated and analyzed for clarithromycin susceptibility and presence of the erm(C) gene. We show that macrolide-resistant strains of S. epidermidis were selected during therapy and that the same resistant strain may persist for 4 years, in the absence of further antimicrobial treatment.
Subject:
[+]
Anti-Bacterial Agents
Antimicrobial Resistance
Case-Control Studies
Clarithromycin
Drug Resistance, Bacterial
Humans
Macrolides
Microbial Sensitivity Tests
Research
Staphylococcal Infections
Staphylococcus Epidermidis
Time Factors
Clarithromycin

Source:
Emerg Infect Dis. 11(9):1389-1393.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:87d05879b64e1afa53afe87b7d4a13194163fc0c8ad0784c8d36f2b570e7bfca
File Type:

Supporting Files

• 	05-0124.nxml	txt
  	license.txt	txt

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