Primate-to-Human Retroviral Transmission in Asia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Jones-Engel, Lisa ; Engel, Gregory A. ; Schillaci, Michael A. ; Rompis, Aida ; Putra, Artha ; Suaryana, Komang Gde ; Fuentes, Agustin ; Beer, Brigitte ; Hicks, Sarah ; White, Robert ; Wilson, Brenda ; Allan, Jonathan S.
• Description:
  We describe the first reported transmission to a human of simian foamy virus (SFV) from a free-ranging population of nonhuman primates in Asia. The transmission of an exogenous retrovirus, SFV, from macaques (Macaca fascicularis) to a human at a monkey temple in Bali, Indonesia, was investigated with molecular and serologic techniques. Antibodies to SFV were detected by Western blotting of serum from 1 of 82 humans tested. SFV DNA was detected by nested polymerase chain reaction (PCR) from the blood of the same person. Cloning and sequencing of PCR products confirmed the virus's close phylogenetic relationship to SFV isolated from macaques at the same temple. This study raises concerns that persons who work at or live around monkey temples are at risk for infection with SFV.
• Subjects:
  Adult Animals DNA, Viral Female Humans Macaca Fascicularis Male Middle Aged Monkey Diseases Phylogeny Research Retroviridae Infections Seroepidemiologic Studies Spumavirus

  More +
• Source:
  Emerg Infect Dis. 11(7):1028-1035.
• Document Type:
  Journal Article
• Place as Subject:
  Indonesia
• Location:
  Asia
• Volume:
  11
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:e98b714c14e291b3a65455a627bf05b6582da96c5b44b5f70fa7248db033e477
• Download URL:
  https://stacks.cdc.gov/view/cdc/15722/cdc_15722_DS1.pdf
• File Type:
  [PDF - 291.87 KB ]