Viral Load Distribution in SARS Outbreak

Chu, Chung-Ming; Cheng, Vincent C.C.; Hung, Ivan F.N.; Chan, Kin-Sang; Tang, Bone S.F.; Tsang, Thomas H.F.; Chan, Kwok-Hung; Yuen, Kwok-Yung

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Viral Load Distribution in SARS Outbreak

Published Date:

Dec 2005

Source:

Emerg Infect Dis. 11(12):1882-1886.

[PDF-126.21 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Chu, Chung-Ming ; Cheng, Vincent C.C. ; Hung, Ivan F.N. ; Chan, Kin-Sang ; Tang, Bone S.F. ; ... More ▼

Description:

An unprecedented community outbreak of severe acute respiratory syndrome (SARS) occurred in the Amoy Gardens, a high-rise residential complex in Hong Kong. Droplet, air, contaminated fomites, and rodent pests have been proposed to be mechanisms for transmitting SARS in a short period. We studied nasopharyngeal viral load of SARS patients on admission and their geographic distribution. Higher nasopharyngeal viral load was found in patients living in adjacent units of the same block inhabited by the index patient, while a lower but detectable nasopharyngeal viral load was found in patients living further away from the index patient. This pattern of nasopharyngeal viral load suggested that airborne transmission played an important part in this outbreak in Hong Kong. Contaminated fomites and rodent pests may have also played a role.

Subject:

[+]

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Main Document Checksum:

[+]

Supporting Files:

	04-0949.nxml	text/plain
	license.txt	text/plain
	04-0949-F1.gif	image/gif
	04-0949-F1.jpg	image/jpeg
	04-0949-F2.gif	image/gif
	04-0949-F2.jpg	image/jpeg
	04-0949-F3.gif	image/gif
	04-0949-F3.jpg	image/jpeg
	04-0949-F4.gif	image/gif
	04-0949-F4.jpg	image/jpeg

No Related Documents.

You May Also Like:

Neutralizing Antibody Response and SARS Severity

Personal Author:

Ho, Mei-Shang; Chen, Wei-Ju; Chen, Hour-Young; Lin, Szu-Fong; Wang, Min-Chin; Di, Jiali; Lu, Yen-Ta; Liu, Ching-Lung; Chang, Shan-Chwen; Chao, Chung-Liang; King, Chwan-Chuen; Chiou, Jeng-Min; Su, Ih-Jen; Yang, Jyh-Yuan;

Published Date:

Nov 2005

Source:

Emerg Infect Dis. 11(11):1730-1737.

Description:

Using the Taiwan nationwide laboratory-confirmed severe acute respiratory syndrome (SARS) database, we analyzed neutralizing antibody in relation to clinical outcomes. With a linear mixed model, neutralizing antibody titer was shown to peak between w...

File Type:

[PDF - 350.84 KB]
Sequential Emergence and Wide Spread of Neutralization Escape Middle East Respiratory Syndrome Coronavirus Mutants, South Korea, 2015

Personal Author:

Kim, Yeon-Sook; Aigerim, Abdimadiyeva; Park, Uni; Kim, Yuri; Rhee, Ji-Young; Choi, Jae-Phil; Park, Wan Beom; Park, Sang Won; Kim, Yeonjae; Lim, Dong-Gyun; Inn, Kyung-Soo; Hwang, Eung-Soo; Choi, Myung-Sik; Shin, Hyoung-Shik; Cho, Nam-Hyuk;

Published Date:

June 17 2019

Source:

Emerg Infect Dis. 25(6):1161-1168

Description:

The unexpectedly large outbreak of Middle East respiratory syndrome in South Korea in 2015 was initiated by an infected traveler and amplified by several "superspreading" events. Previously, we reported the emergence and spread of mutant Middle East ...

File Type:

[PDF - 2.35 MB]
Severe Acute Respiratory Syndrome–associated Coronavirus in Lung Tissue

Personal Author:

Mazzulli, Tony; Farcas, Gabriella A.; Poutanen, Susan M.; Willey, Barbara M.; Low, Donald E.; Butany, Jagdish; Asa, Sylvia L.; Kain, Kevin C.;

Published Date:

Jan 2004

Source:

Emerg Infect Dis. 10(1):20-24.

Description:

Efforts to contain severe acute respiratory syndrome (SARS) have been limited by the lack of a standardized, sensitive, and specific test for SARS-associated coronavirus (CoV). We used a standardized reverse transcription-polymerase chain reaction as...

File Type:

[PDF - 230.40 KB]
Panmicrobial Oligonucleotide Array for Diagnosis of Infectious Diseases

Personal Author:

Palacios, Gustavo; Quan, Phenix-Lan; Jabado, Omar J.; Conlan, Sean; Hirschberg, David L.; Liu, Yang; Zhai, Junhui; Renwick, Neil; Hui, Jeffrey; Hegyi, Hedi; Grolla, Allen; Strong, James E.; Towner, Jonathan S.; Geisbert, Thomas W.; Jahrling, Peter B.; Büchen-Osmond, Cornelia; Ellerbrok, Heinz; Sanchez-Seco, Maria Paz; Lussier, Yves; Formenty, Pierre; Nichol, Stuart T.; Feldmann, Heinz; Briese, Thomas; Lipkin, W. Ian;

Published Date:

Jan 2007

Source:

Emerg Infect Dis. 13(1):73-81.

Description:

To facilitate rapid, unbiased, differential diagnosis of infectious diseases, we designed GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites. Methods for n...

File Type:

[PDF - 372.51 KB]
Detection of SARS Coronavirus in Patients with Suspected SARS

Personal Author:

Chan, Kwok H.; Poon, Leo L.L.M.; Cheng, V.C.C.; Guan, Yi; Hung, I.F.N.; Kong, James; Yam, Loretta Y.C.; Seto, Wing H.; Yuen, Kwok Y.; Peiris, Joseph S. Malik;

Published Date:

Feb 2004

Source:

Emerg Infect Dis. 10(2):294-299.

Description:

Cases of severe acute respiratory syndrome (SARS) were investigated for SARS coronavirus (SARS-CoV) through RNA tests, serologic response, and viral culture. Of 537 specimens from patients in whom SARS was clinically diagnosed, 332 (60%) had SARS-CoV...

File Type:

[PDF - 340.32 KB]