Patterns of Care for Medicare Beneficiaries With Metastatic Prostate Cancer

Details

• Alternative Title:
  Urol Pract
• Personal Author:
  Filson, Christopher P. ; Richards, Thomas B. ; Ekwueme, Donatus U. ; Howard, David H.
• Description:
  Introduction:
  
  Therapeutic options for men with metastatic prostate cancer have increased in the past decade. We studied recent treatment patterns for men with metastatic prostate cancer and how treatment patterns have changed over time.
  
  Methods:
  
  Using the Surveillance, Epidemiology, and End Results–Medicare database, we identified fee-for-service Medicare beneficiaries who either were diagnosed with metastatic prostate cancer or developed metastases following diagnosis, as indicated by the presence of claims with diagnoses codes for metastatic disease, between 2007 and 2017. We evaluated treatment patterns using claims.
  
  Results:
  
  We identified 29,800 men with metastatic disease, of whom 4721 (18.8%) had metastatic disease at their initial diagnosis. The mean age was 77 years, and 77.9% of patients were non-Hispanic White. The proportion receiving antineoplastic agents within 3 years of the index date increased over time (from 9.7% in 2007 to 25.9% in 2017; P < .001). Opioid use within 3 years of prostate cancer diagnosis was stable during 2007 to 2013 (around 73%) but decreased through 2017 to 65.5% (P < .001). Patients diagnosed during 2015 to 2017 had longer median survival (32.6 months) compared to those diagnosed during 2007 to 2010 (26.6 months; P < .001).
  
  Conclusions:
  
  Most metastatic prostate cancer patients do not receive life-prolonging antineoplastic therapies. Improved adoption of effective cancer therapies when appropriate may increase length and quality of survival among metastatic prostate cancer patients.
  
  
• Subjects:
  Aged Antineoplastic Agents Humans Male Medicare Practice Patterns, Physicians' Prostatic Neoplasms SEER Program United States
• Keywords:
  Antineoplastic Therapy Metastasis Physicians’ Practice Patterns Prostate Cancer SEER-Medicare
• Source:
  Urol Pract. 11(3):489-497
• Pubmed ID:
  38640419
• Pubmed Central ID:
  PMC11135654
• Document Type:
  Journal Article
• Funding:
  HHSN261201000140C/CA/NCI NIH HHSUnited States/ ; HHSN261201000035C/CA/NCI NIH HHSUnited States/ ; U48 DP006377/DP/NCCDPHP CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; HHSN261201000035I/CA/NCI NIH HHSUnited States/ ; HHSN261201000034C/CA/NCI NIH HHSUnited States/ ; U58 DP003862/DP/NCCDPHP CDC HHSUnited States/
• Volume:
  11
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:6fc7e8f8be2564b6da56d336109e86e942c25c80b5b1f4bf573d41fcf161c2beb35b89f9684c4ab036dfadcb0d983ab5cd9d3b6a7b08d0154371fb0a12c8b402
• Download URL:
  https://stacks.cdc.gov/view/cdc/157101/cdc_157101_DS1.pdf
• File Type:
  [PDF - 948.26 KB ]