Sporadic Occurrence of Ensitrelvir-Resistant SARS-CoV-2, Japan

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Doi, Akihiro ; Ota, Masayuki ; Saito, Masumichi ; Matsuyama, Shutoku
• Description:
  Using the GISAID EpiCoV database, we identified 256 COVID-19 patients in Japan during March 31-December 31, 2023, who had mutations in the SARS-CoV-2 nonstructural protein 5 conferring ensitrelvir resistance. Ongoing genomic surveillance is required to monitor emergence of SARS-CoV-2 mutations that are resistant to anticoronaviral drugs.
• Subjects:
  Adult Aged Antiviral Agents COVID-19 COVID-19 Drug Treatment Drug Resistance, Viral Female Humans Indazoles Male Middle Aged Mutation SARS-CoV-2 Triazines Triazoles Viral Nonstructural Proteins

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• Keywords:
  Antimicrobial Resistance Coronavirus Coronavirus Disease Ensitrelvir GISAID Japan Respiratory Infections SARS Severe Acute Respiratory Syndrome Coronavirus 2 Viruses Zoonoses

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• Source:
  Emerg Infect Dis. 2024; 30(6):1289-1291
• Pubmed ID:
  38669127
• Pubmed Central ID:
  PMC11138985
• Document Type:
  Journal Article
• Genre:
  Research Letter
• Place as Subject:
  Japan
• Volume:
  30
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:0ca63a3faf797212a3726f38ac504dc5824e15ae30c0bdd4f2e93edff354eb66
• Download URL:
  https://stacks.cdc.gov/view/cdc/156994/cdc_156994_DS1.pdf
• File Type:
  [PDF - 485.52 KB ]