Mycobacterium tuberculosis infection as a zoonotic disease: transmission between humans and elephants.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Michalak, K. ; Austin, C. ; Diesel, S. ; Bacon, M. J. ; Zimmerman, P. ; Maslow, J. N.
• Description:
  Between 1994 and 1996, three elephants from an exotic animal farm in Illinois died of pulmonary disease due to Mycobacterium tuberculosis. In October 1996, a fourth living elephant was culture-positive for M. tuberculosis. Twenty-two handlers at the farm were screened for tuberculosis (TB); eleven had positive reactions to intradermal injection with purified protein derivative. One had smear-negative, culture-positive active TB. DNA fingerprint comparison by IS6110 and TBN12 typing showed that the isolates from the four elephants and the handler with active TB were the same strain. This investigation indicates transmission of M. tuberculosis between humans and elephants.
• Subjects:
  • Animal Husbandry
  • Animals
  • Dna Fingerprinting
  • Disease Outbreaks
  • Elephants
  • Humans
  • Mycobacterium Tuberculosis
  • Polymorphism, Restriction Fragment Length
  • Sputum
  • Tuberculin
  More +
• Source:
  Emerg Infect Dis. 4(2):283-287.
• Document Type:
  Journal Article
• Volume:
  4
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/15492/cdc_15492_DS1.pdf
• File Type:
  [PDF - 176.29 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8f5a417622a8f0bf8dffaac6d0cb7a02b2ab0b574f6d9f718ad43252e11f74ee