Could myocarditis, insulin-dependent diabetes mellitus, and Guillain-Barré syndrome be caused by one or more infectious agents carried by rodents?

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Niklasson, B. ; Hörnfeldt, B. ; Lundman, B.
• Description:
  The numbers of small rodents in northern Sweden fluctuate heavily, peaking every 3 or 4 years. We found that the incidence of Guillain-Barré syndrome and insulin-dependent diabetes mellitus, as well as the number of deaths caused by myocarditis, followed the fluctuations in numbers of bank voles, although with different time lags. An environmental factor, such as an infectious agent, has been suggested for all three diseases. We hypothesize that Guillain-Barré syndrome, myocarditis, and insulin-dependent diabetes mellitus in humans in Sweden are caused by one or more infectious agents carried by small rodents. Also, a group of novel picornaviruses recently isolated from these small rodents is being investigated as the possible etiologic agent(s).
• Subjects:
  Adolescent Adult Animals Arvicolinae Child Diabetes Mellitus, Type 1 Disease Reservoirs Disease Vectors Female Humans Incidence Infection Male Middle Aged Myocarditis Picornaviridae Polyradiculoneuropathy Population Density Zoonoses

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• Source:
  Emerg Infect Dis. 4(2):187-193.
• Document Type:
  Journal Article
• Volume:
  4
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:1fd05a1c7a51c35f1178a148e8d0b19c00099198b29cdab6bcd709fc495d52f4
• Download URL:
  https://stacks.cdc.gov/view/cdc/15482/cdc_15482_DS1.pdf
• File Type:
  [PDF - 601.71 KB ]