Incidence of Stomach, Liver, and Colorectal Cancers by Geography and Social Vulnerability Among American Indian and Alaska Native Populations, 2010–2019

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• Alternative Title:
  Am J Epidemiol
• Personal Author:
  Melkonian, Stephanie C. ; Jim, Melissa A. ; Reza, Avid ; Peipins, Lucy A. ; Haverkamp, Donald ; Said, Nathania ; Sharpe, J. Danielle
• Description:
  Social determinants of health and associated systems, policies, and practices are important drivers of health disparities. American Indian and Alaska Native (AI/AN) populations in the United States have elevated incidence rates of stomach, liver, and colorectal cancers compared with other racial/ethnic groups. In this study, we examined incidence rates of 3 types of gastrointestinal cancer among non-Hispanic AI/AN (NH-AI/AN) and non-Hispanic White (NHW) populations by geographic region and Social Vulnerability Index (SVI) score. Incident cases diagnosed during 2010-2019 were identified from population-based cancer registries linked with the Indian Health Service patient registration databases. Age-adjusted incidence rates (per 100,000 population) for stomach, liver, and colorectal cancers were compared within NH-AI/AN populations and between the NH-AI/AN and NHW populations by SVI score. Rates were higher among NH-AI/AN populations in moderate- and high-SVI-score counties in Alaska, the Southern Plains, and the East than in low-SVI counties. Incidence rates among NH-AI/AN populations were elevated when compared with NHW populations by SVI category. Results indicated that higher social vulnerability may drive elevated cancer incidence among NH-AI/AN populations. Additionally, disparities between NH-AI/AN and NHW populations persist even when accounting for SVI. Exploring social vulnerability can aid in designing more effective interventions to address root causes of cancer disparities among AI/AN populations.
• Subjects:
  American Indian Or Alaska Native Colorectal Neoplasms Geography Humans Incidence Liver Neoplasms Racial Groups Registries Social Vulnerability Stomach Neoplasms United States

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• Keywords:
  Alaska Natives American Indians Cancer Incidence Health Disparities Social Determinants Of Health Social Vulnerability Index
• Source:
  Am J Epidemiol. 193(1):58-74
• Pubmed ID:
  37823258
• Pubmed Central ID:
  PMC10990004
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  193
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:3cc07c132f01b3330400971a3578777cf84c13e26601da81be3815a8bf2d109feae3fdf0ae8c049889b5ef5f58d267b4ba92c953b11073ac9b361c3e8d6c5b9f
• Download URL:
  https://stacks.cdc.gov/view/cdc/154075/cdc_154075_DS1.pdf
• File Type:
  [PDF - 1.09 MB ]