Cancer disparities among non-Hispanic urban American Indian and Alaska Native populations in the United States, 1999–2017

Details

• Alternative Title:
  Cancer
• Personal Author:
  Melkonian, Stephanie C. ; Jim, Melissa A. ; Pete, Dornell ; Poel, Amy ; Dominguez, Adrian E. ; Echo-Hawk, Abigail ; Zhang, Stephanie ; Wilson, Reda J. ; Haverkamp, Donald ; Petras, Lindsey ; Pohlenz, Ashley
• Description:
  BACKGROUND:
  
  Disparities in cancer incidence have not been described for urban American Indian/Alaska Native (AI/AN) populations. The purpose of the present study was to examine incidence rates (2008–2017) and trends (1999–2017) for leading cancers in urban non-Hispanic AI/AN (NH AI/AN) compared to non-Hispanic White (NHW) populations living in the same urban areas.
  
  METHODS:
  
  Incident cases from population-based cancer registries were linked with the Indian Health Service patient registration database for improved racial classification of NH AI/AN populations. This study was limited to counties in Urban Indian Health Organization service areas. Analyses were conducted by geographic region. Age-adjusted rates (per 100,000) and trends (joinpoint regression) were calculated for leading cancers.
  
  RESULTS:
  
  Rates of colorectal, liver, and kidney cancers were higher overall for urban NH AI/AN compared to urban NHW populations. By region, rates of these cancers were 10% to nearly 4 times higher in NH AI/AN compared to NHW populations. Rates for breast, prostate, and lung cancer were lower in urban NH AI/AN compared to urban NHW populations. Incidence rates for kidney, liver, pancreatic, and breast cancers increased from 2% to nearly 7% annually between 1999 to 2017 in urban NH AI/AN populations.
  
  CONCLUSIONS:
  
  This study presents cancer incidence rates and trends for the leading cancers among urban NH AI/AN compared to urban NHW populations for the first time, by region, in the United States. Elevated risk of certain cancers among urban NH AI/AN populations and widening cancer disparities highlight important health inequities and missed opportunities for cancer prevention in this population.
  
  
• Subjects:
  American Indian Or Alaska Native Health Status Disparities Humans Incidence Neoplasms Registries United States
• Keywords:
  Alaska Native American Indian Cancer Incidence Health Disparity Trends Urban
• Source:
  Cancer. 128(8):1626-1636
• Pubmed ID:
  35119703
• Pubmed Central ID:
  PMC10929659
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  128
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:fbbb4dd4b89ab7f2c8cd5b71f897cfcf6220b1071e56f1476f9294a1a1927064
• Download URL:
  https://stacks.cdc.gov/view/cdc/151683/cdc_151683_DS1.pdf
• File Type:
  [PDF - 592.97 KB ]