How many genes underlie the occurrence of common complex diseases in the population?
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10/01/2005
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Description:Journal article co-authored by the Public Health Genomics Branch. In this analysis, the authors estimated the number of disease susceptibility genes needed to account for varying population attributable fractions of a common complex disease, taking into account the genotype prevalence, risk ratios for individual
genes, and the model of gene–gene interactions.
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Main Document Checksum:urn:sha256:019df180ee612a4c7bc21bce46f89ca70574b948db5bfb16c452339f93474481
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