How many genes underlie the occurrence of common complex diseases in the population?
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How many genes underlie the occurrence of common complex diseases in the population?

  • 10/01/2005

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  • Description:
    Journal article co-authored by the Public Health Genomics Branch. In this analysis, the authors estimated the number of disease susceptibility genes needed to account for varying population attributable fractions of a common complex disease, taking into account the genotype prevalence, risk ratios for individual

    genes, and the model of gene–gene interactions.

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