PopART (HPTN 071)

Details

• Corporate Authors:
  National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.). Division of HIV/AIDS Prevention
• Description:
  PopART (HPTN 071) is a community-randomized trial of a combination HIV prevention intervention designed to reduce HIV incidence in urban and peri-urban communities in Zambia and Western Cape Province, South Africa. The comparison consisted of two intervention groups (Group A and Group B) to receive the PopART intervention and a standard of care (Group C). The communities randomized to PopART (Groups A and B), utilized specially trained community HIV care providers (CHiPs) to visit households within the community at least once annually during the four -year intervention period. During the home visit, the following services are offered to residents: HIV education and prevention information; HIV counseling and testing; and referrals to the local government clinic for HIV care and provision of antiretroviral treatment (ART) according to the local guidelines (specific to Group B) for participants who tested positive for HIV. Additional services include support for ART retention and adherence, symptom screening for tuberculosis (TB) and sexually transmitted infections (STI), with referrals for diagnosis and treatment, and referrals for male circumcision (for HIV negative males), antenatal care (for HIV positive pregnant women), reproductive health, and family planning services. Condoms are also promoted and provided during home visits. At the local government clinic, in Group A communities, HIV positive individuals are offered universal ART, while in Group B communities, ART was initially offered according to local guidelines, but then universal ART was offered at the study midpoint because of updated WHO guidelines for ART initiation .
• Subjects:
  Acquired Immunodeficiency Syndrome Acquired Immunodeficiency Syndrome / Epidemiology Data Interpretation, Statistical Epidemics Epidemiological Monitoring HIV Public Health Surveillance Statistics Tables
• Keywords:
  DHP_HIV_Reports PRS Project HIV Compendium
• Series:
  Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention
• Publisher:
  Centers for Disease Control and Prevention (CDC) (U.S.)
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  United States
• Rights:
  Public Domain
• CIO:
  National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention (NCHHSTP)
• Division:
  DHP - Division of HIV/AIDS Prevention
• Topic:
  Diseases & Conditions
• Location:
  North America
• Collection(s):
  Infectious Diseases
• Main Document Checksum:
  urn:sha-512:8d89971a3a3a43783cba56551f8abd4e75199978dc68162f96f5b3414ab6e3acdf33e69403006db87e0d223370894900f2fc2bcd484134dd09f2e9f494010b8e
• Download URL:
  https://stacks.cdc.gov/view/cdc/149620/cdc_149620_DS1.pdf
• File Type:
  [PDF - 379.04 KB ]