Person-to-Person Transmission of Andes Virus

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Martinez, Valeria P. ; Bellomo, Carla ; San Juan, Jorge ; Pinna, Diego ; Forlenza, Raul ; Elder, Malco ; Padula, Paula J.
• Description:
  Despite the fact that rodents are considered to be the infectious source of hantavirus for humans, another route of transmission was demonstrated. Andes virus (ANDV) has been responsible for most of the cases recorded in Argentina. Person-to-person transmission of ANDV Sout lineage was described during an outbreak of hantavirus pulmonary syndrome in southwest Argentina. In this study, we analyzed 4 clusters that occurred in 2 disease-endemic areas for different ANDV lineages. We found new evidence of interhuman transmission for ANDV Sout lineage and described the first event in which another lineage, ANDV Cent BsAs, was implicated in this mechanism of transmission. On the basis of epidemiologic and genetic data, we concluded that person-to-person spread of the virus likely took place during the prodromal phase or shortly after it ended, since close and prolonged contact occurred in the events analyzed here, and the incubation period was 15-24 days.
• Subjects:
  Adolescent Adult Andes Virus Argentina Child Clusters Disease Outbreaks Female Hantavirus Hantavirus Pulmonary Syndrome Humans Infectious Source Male Middle Aged Person To Person Transmission Research Time Factors Virus Spread

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• Source:
  Emerg Infect Dis. 11(12):1848-1853.
• Document Type:
  Journal Article
• Volume:
  11
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:b64124d29f64d9cf11f1c8a2620dd5d3deec8e1633664ba922ea7928808efdc6
• Download URL:
  https://stacks.cdc.gov/view/cdc/14768/cdc_14768_DS1.pdf
• File Type:
  [PDF - 167.90 KB ]