Human Coronavirus NL63, France

Vabret, Astrid; Mourez, Thomas; Dina, Julia; van der Hoek, Lia; Gouarin, Stéphanie; Petitjean, Joëlle; Brouard, Jacques; Freymuth, François

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Human Coronavirus NL63, France

Aug 2005
By Vabret, Astrid ; Mourez, Thomas ; Dina, Julia ; ...
Source: Emerg Infect Dis. 11(8):1225-1229.

[PDF-240.19 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Vabret, Astrid ; Mourez, Thomas ; Dina, Julia ; van der Hoek, Lia ; Gouarin, Stéphanie ; ... More +

Vabret, Astrid ; Mourez, Thomas ; Dina, Julia ; van der Hoek, Lia ; Gouarin, Stéphanie ; Petitjean, Joëlle ; Brouard, Jacques ; Freymuth, François Less -
Description:

The human coronavirus NL63 (HCoV-NL63) was first identified in The Netherlands, and its circulation in France has not been investigated. We studied HCoV-NL63 infection in hospitalized children diagnosed with respiratory tract infections. From November 2002 to April 2003, we evaluated 300 respiratory specimens for HCoV-NL63. Of the 300 samples, 28 (9.3%) were positive for HCoV-NL63. The highest prevalence was found in February (18%). The main symptoms were fever (61%), rhinitis (39%), bronchiolitis (39%), digestive problems (33%), otitis (28%), pharyngitis (22%), and conjunctivitis (17%). A fragment of the spike protein gene was sequenced to determine the variety of circulating HCoV-NL63. Phylogenetic analysis indicated that strains with different genetic markers cocirculate in France.
Subjects:

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Adolescent Amino Acid Sequence Base Sequence Child Child, Preschool Coronavirus Coronavirus Infections Humans Infant Phylogeny Respiratory Tract Infections Retrospective Studies Reverse Transcriptase Polymerase Chain Reaction Rna, Viral Sequence Alignment Sequence Analysis, DNA
Source:

Emerg Infect Dis. 11(8):1225-1229.
Document Type:

Journal Article
Place as Subject:

France
Volume:

11
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:a7cb2a5e903c32bd31b203475a2469b866417038e51d146c04da20f711c4b1b2
Download URL:

https://stacks.cdc.gov/view/cdc/14757/cdc_14757_DS1.pdf
File Type:

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