Novel Avian Influenza H7N3 Strain Outbreak, British Columbia

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Hirst, Martin ; Astell, Caroline R. ; Griffith, Malachi ; Coughlin, Shaun M. ; Moksa, Michelle ; Zeng, Thomas ; Smailus, Duane E. ; Holt, Robert A. ; Jones, Steven ; Marra, Marco A. ; Petric, Martin ; Krajden, Mel ; Lawrence, David ; Mak, Annie ; Chow, Ron ; Skowronski, Danuta M. ; Tweed, S. Aleina ; Goh, SweeHan ; Brunham, Robert C. ; Robinson, John ; Bowes, Victoria ; Sojonky, Ken ; Byrne, Sean K. ; Li, Yan ; Kobasa, Darwyn ; Booth, Tim ; Paetzel, Mark
• Description:
  Genome sequences of chicken (low pathogenic avian influenza [LPAI] and highly pathogenic avian influenza [HPAI]) and human isolates from a 2004 outbreak of H7N3 avian influenza in Canada showed a novel insertion in the HA0 cleavage site of the human and HPAI isolate. This insertion likely occurred by recombination between the hemagglutination and matrix genes in the LPAI virus.
• Subjects:
  Amino Acid Sequence Animals Chickens Disease Outbreaks Humans Influenza A Virus Influenza In Birds Models, Molecular Molecular Sequence Data Mutagenesis, Insertional Protein Conformation Sequence Alignment Viral Proteins

  More +
• Source:
  Emerg Infect Dis. 10(12):2192-2195.
• Document Type:
  Journal Article
• Place as Subject:
  British Columbia, Canada
• Volume:
  10
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:8302635cfb96dc8ca42fe475934fc8d79377881cc9c8e6f9f84d882695f891e2
• Download URL:
  https://stacks.cdc.gov/view/cdc/14707/cdc_14707_DS1.pdf
• File Type:
  [PDF - 389.98 KB ]