Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Oteo, Jesús ; Lázaro, Edurne ; de Abajo, Francisco J. ; Baquero, Fernando ; Campos, José
Oteo, Jesús ; Lázaro, Edurne ; de Abajo, Francisco J. ; Baquero, Fernando ; Campos, José Less -
Corporate Authors:
Spanish members of EARSS
Description:
Surveillance System. A network of 32 Spanish hospitals, serving approximately 9.6 million persons, submitted antimicrobial-susceptibility data on 7,098 invasive Escherichia coli species (2001-2003). Resistance to ampicillin, cotrimoxazole, ciprofloxacin, gentamicin, and tobramycin was found at rates of 59.9%, 32.6%, 19.3%, 6.8%, and 5.3%, respectively. Resistance to multiple drugs increased from 13.8% in 2001 to 20.6% in 2003 (p <0.0001). Antimicrobial consumption data were obtained from the Spanish National Health System. In spite of decreased cephalosporin and beta-lactam use, overall extended-spectrum beta-lactamase production increased from 1.6% (2001) to 4.1% (2003) (p <0.0001), mainly due to the rising prevalence of cefotaximases. Resistance to ciprofloxacin significantly increased, mostly in community-onset infections, which coincided with a rise in community quinolone use. Cotrimoxazole resistance remained stable at approximately 30%, even though its use was dramatically reduced.
Subject:
[+]
Anti-Bacterial Agents
Antimicrobial Susceptibility
Drug Resistance, Bacterial
Drug Resistance, Multiple, Bacterial
Escherichia Coli
Escherichia Coli Infections
Humans
Invasive Pathogens
Prospective Studies
Research
Spain
Time Factors

Source:
Emerg Infect Dis. 11(4):546-553.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:776248d8a70f0b3bd135af724da7d46f6212b4dcff93c0f23418b0a8b5dab964
File Type:

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