Antimicrobial-resistant Invasive Escherichia coli, Spain

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Oteo, Jesús ; Lázaro, Edurne ; de Abajo, Francisco J. ; Baquero, Fernando ; Campos, José
• Corporate Authors:
  Spanish members of EARSS
• Description:
  Surveillance System. A network of 32 Spanish hospitals, serving approximately 9.6 million persons, submitted antimicrobial-susceptibility data on 7,098 invasive Escherichia coli species (2001-2003). Resistance to ampicillin, cotrimoxazole, ciprofloxacin, gentamicin, and tobramycin was found at rates of 59.9%, 32.6%, 19.3%, 6.8%, and 5.3%, respectively. Resistance to multiple drugs increased from 13.8% in 2001 to 20.6% in 2003 (p <0.0001). Antimicrobial consumption data were obtained from the Spanish National Health System. In spite of decreased cephalosporin and beta-lactam use, overall extended-spectrum beta-lactamase production increased from 1.6% (2001) to 4.1% (2003) (p <0.0001), mainly due to the rising prevalence of cefotaximases. Resistance to ciprofloxacin significantly increased, mostly in community-onset infections, which coincided with a rise in community quinolone use. Cotrimoxazole resistance remained stable at approximately 30%, even though its use was dramatically reduced.
• Subjects:
  Anti-Bacterial Agents Antimicrobial Susceptibility Drug Resistance, Bacterial Drug Resistance, Multiple, Bacterial Escherichia Coli Escherichia Coli Infections Humans Invasive Pathogens Prospective Studies Research Spain Time Factors

  More +
• Source:
  Emerg Infect Dis. 11(4):546-553.
• Document Type:
  Journal Article
• Volume:
  11
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:776248d8a70f0b3bd135af724da7d46f6212b4dcff93c0f23418b0a8b5dab964
• Download URL:
  https://stacks.cdc.gov/view/cdc/14702/cdc_14702_DS1.pdf
• File Type:
  [PDF - 155.39 KB ]