Identifying Rodent Hantavirus Reservoirs, Brazil

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Suzuki, Akemi ; Bisordi, Ivani ; Levis, Silvana ; Garcia, Jorge ; Pereira, Luiz E. ; Souza, Renato P. ; Sugahara, Teresa K.N. ; Pini, Noemi ; Enria, Delia ; Souza, Luiza T.M.
• Description:
  We describe the genetic analysis of samples from hantavirus pulmonary syndrome (HPS) patients from southern and southeastern states of Brazil and rodents captured at the presumed site of infection of these patients. A total of 65 samples that were antibody-positive for Sin Nombre or Laguna Negra virus by enzyme-linked immunosorbent assay were processed by nested reverse transcription-polymerase chain reaction (RT-PCR) by using several primer combinations in the M and S genome segments. PCR products were amplified and sequenced from samples from 11 HPS patient and 7 rodent samples. Phylogenetic analysis of nucleotide sequence differences showed the cocirculation of Araraquara and Juquitiba-like viruses, previously characterized from humans. Our genetic data indicate that Araraquara virus is associated with Bolomys lasiurus (hairy-tailed Bolo mouse) and the Juquitiba-like virus is associated with Oligoryzomys nigripes (black-footed pigmy rice rat).
• Subjects:
  Adult Animals Disease Reservoirs Female Hantavirus Hantavirus Pulmonary Syndrome Humans Male Middle Aged Phylogeny Reverse Transcriptase Polymerase Chain Reaction RNA, Viral Rodentia

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• Source:
  Emerg Infect Dis. 10(12):2127-2134.
• Document Type:
  Journal Article
• Place as Subject:
  Brazil
• Volume:
  10
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6271686dca49abb6e06785b483b1d4c0d564157bbde21fbe68c02028eead64fd
• Download URL:
  https://stacks.cdc.gov/view/cdc/14645/cdc_14645_DS1.pdf
• File Type:
  [PDF - 280.70 KB ]