Serotype III Streptococcus agalactiae from Bovine Milk and Human Neonatal Infections1

Bohnsack, John F.; Whiting, April A.; Martinez, Gabriela; Jones, Nicola; Adderson, Elisabeth E.; Detrick, Shauna; Blaschke-Bonkowsky, Anne J.; Bisharat, Naiel; Gottschalk, Marcelo

i

Serotype III Streptococcus agalactiae from Bovine Milk and Human Neonatal Infections1

Supporting Files Public Domain

Aug 2004
By Bohnsack, John F. ; Whiting, April A. ; Martinez, Gabriela ; ...

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Bohnsack, John F. ; Whiting, April A. ; Martinez, Gabriela ; Jones, Nicola ; Adderson, Elisabeth E. ; Detrick, Shauna ; Blaschke-Bonkowsky, Anne J. ; Bisharat, Naiel ; Gottschalk, Marcelo
Description:

Streptococcus agalactiae (group B streptococcus [GBS]) causes invasive human infections and bovine mastitis. This study examined the genetic relationship between bovine and human serotype III GBS by using molecular techniques that classify human serotype III GBS into four distinct phylogenetic lineages. Bovine serotype III GBS were largely contained in two lineages, which are distinct from the two major lineages (restriction digest types III-2 and III-3) that infect human neonates. One of the bovine lineages closely resembles the human III-1 lineage, whose members occasionally cause human neonatal infections. The bovine strains in the other lineage characteristically have an initiation factor IF2 gene (infB) H allele and multilocus sequence types that are not found in human GBS strains. Evidence suggests that this "H allele" lineage is related to the human III-3 lineage. These results support the assertion that human and bovine GBS are largely unrelated and provide further insight into the genetic relation between human and bovine GBS.
Subjects:

Alleles Animals Bovine Mastitis Cattle Cattle Diseases Female Group B Streptococcus Humans Infant, Newborn InfB Milk Molecular Sequence Data Neonatal Sepsis Phylogeny Pregnancy Pregnancy Complications, Infectious Prokaryotic Initiation Factor-2 Research Sequence Analysis, DNA Serotyping Streptococcal Infections Streptococcus Agalactiae
Source:

Emerg Infect Dis. 10(8):1412-1419.
Document Type:

Journal Article
Volume:

10
Issue:

8
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:6cf0cb21b0e5898ecff0a33586cc06ae02136064217a10f854ba8785a4c3e224
Download URL:

https://stacks.cdc.gov/view/cdc/14530/cdc_14530_DS1.pdf
File Type:

[PDF - 216.94 KB ]

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.