Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins

Sandoval, Carolyn; Walter, Stephen D.; McGeer, Allison; Simor, Andrew E.; Bradley, Suzanne F.; Moss, Lorraine M.; Loeb, Mark B.

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Nursing Home Residents and Enterobacteriaceae Resistant to Third-Generation Cephalosporins

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Jun 2004
By Sandoval, Carolyn ; Walter, Stephen D. ; McGeer, Allison ; ...

File Language:

English

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Alternative Title:

Emerg Infect Dis
Personal Author:

Sandoval, Carolyn ; Walter, Stephen D. ; McGeer, Allison ; Simor, Andrew E. ; Bradley, Suzanne F. ; Moss, Lorraine M. ; Loeb, Mark B.
Description:

Limited data identify the risk factors for infection with Enterobacteriaceae resistant to third-generation cephalosporins among residents of long-term-care facilities. Using a nested case-control study design, nursing home residents with clinical isolates of Enterobacteriaceae resistant to third-generation cephalosporins were compared to residents with isolates of Enterobacteriaceae susceptible to third-generation cephalosporins. Data were collected on antimicrobial drug exposure 10 weeks before detection of the isolates, facility-level demographics, hygiene facilities, and staffing levels. Logistic regression models were built to adjust for confounding variables. Twenty-seven case-residents were identified and compared to 85 controls. Exposure to any cephalosporin (adjusted odds ratio [OR] 4.0, 95% confidence interval [CI] 1.2 to 13.6) and log percentage of residents using gastrostomy tubes within the nursing home (adjusted OR 3.9, 95% CI 1.3 to 12.0) were associated with having a clinical isolate resistant to third-generation cephalosporins.
Subjects:

Aged Anti-Bacterial Agents Case-Control Studies Cephalosporins Drug Resistance, Bacterial Enterobacteriaceae Enterobacteriaceae Infections Humans Logistic Models Microbial Sensitivity Tests Multivariate Analysis Nursing Homes Research Risk Factors
Source:

Emerg Infect Dis. 10(6):1050-1055.
Document Type:

Journal Article
Place as Subject:

Canada ; United States
Location:

North America
Volume:

10
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:7760d6232fed4862fe7e35f977f93bacc55558ed54c3141e89d2a40e4fdede97
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https://stacks.cdc.gov/view/cdc/14469/cdc_14469_DS1.pdf
File Type:

[PDF - 76.47 KB ]

03-0662.nxml

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