Environmental Exposure and Leptospirosis, Peru

Johnson, Michael A.S.; Smith, Hannah; Joseph, Priya; Gilman, Robert H.; Bautista, Christian T.; Campos, Kalina J.; Cespedes, Michelle; Klatsky, Peter; Vidal, Carlos; Terry, Hilja; Calderon, Maritza M.; Coral, Carlos; Cabrera, Lilia; Parmar, Paminder S.; Vinetz, Joseph M.

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Environmental Exposure and Leptospirosis, Peru

Supporting Files Public Domain

Jun 2004
By Johnson, Michael A.S. ; Smith, Hannah ; Joseph, Priya

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Johnson, Michael A.S. ; Smith, Hannah ; Joseph, Priya ; Gilman, Robert H. ; Bautista, Christian T. ; Campos, Kalina J. ; Cespedes, Michelle ; Klatsky, Peter ; Vidal, Carlos ; Terry, Hilja ; Calderon, Maritza M. ; Coral, Carlos ; Cabrera, Lilia ; Parmar, Paminder S. ; Vinetz, Joseph M.
Description:

Human infection by leptospires has highly variable clinical manifestations, which range from subclinical infection to fulminant disease. We conducted a population-based, cross-sectional seroepidemiologic study in Peru to determine potential relationships of environmental context to human exposure to Leptospira and disease associated with seroconversion. Three areas were studied: a flooded, urban slum in the Peruvian Amazon city of Iquitos; rural, peri-Iquitos villages; and a desert shantytown near Lima. Seroprevalence in Belen was 28% (182/650); in rural areas, 17% (52/316); and in a desert shantytown, 0.7% (1/150). Leptospira-infected peridomestic rats were found in all locales. In Belen, 20 (12.4%) of 161 patients seroconverted between dry and wet seasons (an incidence rate of 288/1,000). Seroconversion was associated with history of febrile illness; severe leptospirosis was not seen. Human exposure to Leptospira in the Iquitos region is high, likely related both to the ubiquity of leptospires in the environment and human behavior conducive to transmission from infected zoonotic sources.
Subjects:
Source:

Emerg Infect Dis. 10(6):1016-1022.
Document Type:

Journal Article
Place as Subject:

Peru
Volume:

10
Issue:

6
Download URL:

https://stacks.cdc.gov/view/cdc/14468/cdc_14468_DS1.pdf
File Type:

[PDF - 207.01 KB]
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:78193e58632d052e122de8fe56cc5e0acba72545243f4fba11d49486ff0add7a

File Language:

English

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