Sporadic Cryptosporidiosis Case-Control Study with Genotyping

Hunter, Paul R.; Hughes, Sara; Woodhouse, Sarah; Syed, Qutub; Verlander, Neville Q.; Chalmers, Rachel M.; Morgan, Kenton; Nichols, Gordon; Beeching, Nick; Osborn, Keith

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Sporadic Cryptosporidiosis Case-Control Study with Genotyping

Supporting Files Public Domain

Jul 2004
By Hunter, Paul R. ; Hughes, Sara ; Woodhouse, Sarah ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Hunter, Paul R. ; Hughes, Sara ; Woodhouse, Sarah ; Syed, Qutub ; Verlander, Neville Q. ; Chalmers, Rachel M. ; Morgan, Kenton ; Nichols, Gordon ; Beeching, Nick ; Osborn, Keith
Description:

We report a case-control study of sporadic cryptosporidiosis with genotyping of isolates from case-patients. A postal questionnaire was completed by 427 patients and 427 controls. We obtained genotyping data on isolates from 191 patients; 115 were Cryptosporidium hominis, and 76 were C. parvum. When all cryptosporidiosis cases were analyzed, three variables were strongly associated with illness: travel outside the United Kingdom, contact with another person with diarrhea, and touching cattle. Eating ice cream and eating raw vegetables were both strongly negatively associated with illness. Helping a child <5 years of age to use the toilet and the number of glasses of tap water drunk at home each day were also independently positively associated with risk. Eating tomatoes was negatively associated. For C. hominis infections, the strongly significant risk factors were travel abroad and changing diapers of children <5 years of age. For C. parvum, eating raw vegetables and eating tomatoes were strongly negatively associated with illness; touching farm animals was associated with illness.
Subjects:

Adolescent Adult Aged Aged, 80 And Over Age Distribution Animals Case-Control Studies Cattle Child Child, Preschool Cryptosporidium Female Genotype Humans Infant Infant, Newborn Male Middle Aged Questionnaires Risk Factors
Source:

Emerg Infect Dis. 10(7):1241-1249.
Document Type:

Journal Article
Place as Subject:

England ; Wales
Volume:

10
Issue:

7
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:d5a346e199e7b9255f2751d0cbfc5e3fa4e84e7cd6572fb5f28a4a3c8832615c
Download URL:

https://stacks.cdc.gov/view/cdc/14444/cdc_14444_DS1.pdf
File Type:

[PDF - 288.35 KB ]

File Language:

English

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