Immunofluorescence Assay for Serologic Diagnosis of SARS

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Chan, Paul K. S. ; Ng, King-Cheung ; Chan, Rickjason C. W. ; Lam, Rebecca K. Y. ; Chow, Viola C. Y. ; Hui, Mamie ; Wu, Alan ; Lee, Nelson ; Yap, Florence H.Y. ; Cheng, Frankie W. T. ; Sung, Joseph J. Y. ; Tam, John S.
  More +
• Description:
  We evaluated an indirect immunofluorescence assay based on virus-infected cells for detecting anti-severe acute respiratory syndrome-associated coronavirus (SARS-CoV) immunoglobulin (Ig) G antibody. All confirmed SARS cases demonstrated seroconversion or fourfold rise in IgG antibody titer; no control was positive. Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection.
• Subjects:
  • Dispatch
  • coronavirus
  • diagnosis
  • serology
  • sensitivity
  • specificity
  • severe acute respiratory syndrome
  • SARS
  • Adolescent
  • Adult
  More +
• Source:
  Emerg Infect Dis. 10(3):530-532.
• Document Type:
  Journal Article
• Volume:
  10
• Issue:
  3
• Download URL:
  https://stacks.cdc.gov/view/cdc/14408/cdc_14408_DS1.pdf
• File Type:
  [PDF - 96.04 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4b618b921088bb9e2702bfbefff651b2a91429059a9b65a38b9c8747308be9ed