Limited Spread of Penicillin-Nonsusceptible Pneumococci, Skåne County, Sweden

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Melander, Eva ; Hansson, Hans-Bertil ; Mölstad, Sigvard ; Persson, Kristina ; Ringberg, Håkan
• Description:
  In response to increasing frequencies of penicillin-nonsusceptible pneumococci (PNSP), for which the MIC of penicillin was >0.12 mg/L, in Skåne County, southern Sweden, national recommendations were initiated in 1995 to limit the spread of pneumococci with high MICs (> or =0.5 mg/L) of penicillin (PRP), especially among children of preschool age. Traditional communicable disease control measures were combined with actions against inappropriate antimicrobial drug use. During the first 6 years that these recommendations were applied in Skåne County, the average frequency of penicillin-resistant pneumococci has been stable at =2.6%, as has the average PNSP frequency (7.4%). However, PNSP have been unevenly distributed in the county, with the highest frequencies in the southwest. Simultaneously, the rate of antimicrobial drug use for children <6 years of age was reduced by 20%. Thus the spread of PNSP between and within the municipalities in the county has been limited.
• Subjects:
  Anti-Bacterial Agents Antibiotics Carrier State Child, Preschool Children Communicable Disease Control Community Drug Resistance Drug Utilization Humans Infant Intervention Studies Microbial Penicillin Resistance Pneumococcal Infections Prevalence Research Streptococcus Pneumonia Streptococcus Pneumoniae Sweden

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• Source:
  Emerg Infect Dis. 10(6):1082-1087.
• Document Type:
  Journal Article
• Volume:
  10
• Issue:
  6
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d31ad8107f0b054f088d8417e8c1e538b2bbeaa515fb6f9540ebce4d3d3a6dc6
• Download URL:
  https://stacks.cdc.gov/view/cdc/14405/cdc_14405_DS1.pdf
• File Type:
  [PDF - 118.04 KB ]