Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid0912.030270
Personal Author:
Linke, Michael J. ; Rebholz, Sandy ; Collins, Margaret ; Tanaka, Reiko ; Cushion, Melanie T.
Linke, Michael J. ; Rebholz, Sandy ; Collins, Margaret ; Tanaka, Reiko ; Cushion, Melanie T. Less -
Description:
The progression of Pneumocystis carinii pneumonia was temporally monitored and quantified by real-time polymerase chain reaction of P. carinii-specific DNA in oral swabs and lung homogenates from infected rats. DNA levels correlated with the number of P. carinii organisms in the rats' lungs, as enumerated by microscopic methods. This report is the first of a noninvasive, antemortem method that can be used to monitor infection in a host over time.
Subject:
[+]
Animals
Bronchoalveolar Lavage
Dispatch
DNA, Fungal
DNA, Mitochondrial
Fungal
Immunocompromised Host
Lung
Lung Diseases
Male
Mouth Mucosa
Pneumocystis Carinii
Pneumonia
Pneumonia, Pneumocystis
Polymerase Chain Reaction
Rats
Rats, Long-Evans
Statistics, Nonparametric
Polymerase Chain Reaction

Source:
Emerg Infect Dis. 9(12):1613-1616.
Document Type:
Journal Article
Funding:
R01 AI29839-10/AI/NIAID NIH HHS/United States
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:a70437a8698f3280f81fedd3bdbdd369160be18735264e48c6ea1ae6fb2d14f4
File Type:

Supporting Files

• 	03-0270-F.gif	gif
  	03-0270-F.jpg	jpeg
  	03-0270.nxml	txt
  	license.txt	txt

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