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Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes
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Mar 2004
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Source: Emerg Infect Dis. 10(3):514-517.
[PDF-151.64 KB]
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Alternative Title:Emerg Infect Dis
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Description:We correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP), macrolide-resistant S. pneumoniae (MRSP), and macrolide-resistant S. pyogenes (MRGAS) in 20 countries. Total antibiotic use was correlated with PNSP (r = 0.75; p < 0.001), as was macrolide use with MRSP (r = 0.88; p < 0.001) and MRGAS (r = 0.71; p = 0.004). Streptococcal resistance is directly associated with antibiotic selection pressure on a national level.
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Volume:10
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Issue:3
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