Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes

Albrich, Werner C.; Monnet, Dominique L.; Harbarth, Stephan

doi:10.3201/eid1003.030252

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Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes

Published Date:

Mar 2004

Publisher's site:

http://dx.doi.org/10.3201/eid1003.030252 New Site Icon

Source:

Emerg Infect Dis. 10(3):514-517.

[PDF - 151.64 KB]

Details:

Personal Authors:

Albrich, Werner C. ; Monnet, Dominique L. ; Harbarth, Stephan ;

Keywords:

[+]

Description:

We correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP), macrolide-resistant S. pneumoniae (MRSP), and macrolide-resistant S. pyogenes (MRGAS) in 20 countries. Total antibiotic use was correlated with PNSP (r = 0.75; p < 0.001), as was macrolide use with MRSP (r = 0.88; p < 0.001) and MRGAS (r = 0.71; p = 0.004). Streptococcal resistance is directly associated with antibiotic selection pressure on a national level.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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