Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Lan, Nguyen Thi Ngoc ; Lien, Hoang Thi Kim ; Tung, Le B. ; Borgdorff, Martien W. ; Kremer, Kristin ; van Soolingen, Dick
• Description:
  Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).
• Subjects:
  Adolescent Adult Aged Antitubercular Agents Case-Control Studies Dna, Bacterial Female Genotype Humans Male Middle Aged Polymorphism, Restriction Fragment Length Recurrence Sputum Treatment Failure Tuberculosis

  More +
• Source:
  Emerg Infect Dis. 9(12):1633-1635.
• Document Type:
  Journal Article
• Place as Subject:
  Vietnam
• Volume:
  9
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:00802002ec89a921dd2711ad583b04b3413f4b3086f3bd7d53fbd88b01a03cca
• Download URL:
  https://stacks.cdc.gov/view/cdc/14281/cdc_14281_DS1.pdf
• File Type:
  [PDF - 194.75 KB ]