Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam
Published Date:Dec 2003
Source:Emerg Infect Dis. 9(12):1633-1635.
Polymorphism, Restriction Fragment Length
Description:Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).
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