Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Pottumarthy, Sudha ; Moland, Ellen Smith ; Juretschko, Stefan ; Swanzy, Susan R. ; Thomson, Kenneth S. ; ... More +
Pottumarthy, Sudha ; Moland, Ellen Smith ; Juretschko, Stefan ; Swanzy, Susan R. ; Thomson, Kenneth S. ; Fritsche, Thomas R. Less -
Description:
An imipenem-resistant Enterobacter cloacae isolate was recovered from the blood of a patient with a hematologic malignancy. Analytical isoelectric focusing, inhibitor studies, hydrolysis, induction assays, and molecular sequencing methods confirmed the presence of a NmcA carbapenem-hydrolyzing enzyme. This first report of NmcA detected in North America warrants further investigation into its distribution and clinical impact.
Subject:
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Adult Antibiotic Resistance Bacterial Proteins Beta-lactamase Beta-Lactamases Carbapenem Dispatch Drug Resistance, Microbial Enterobacter Cloacae Humans Imipenem Isoelectric Focusing Leukemia, Myeloid Male Microbial Sensitivity Tests
Source:
Emerg Infect Dis. 9(8):999-1002
Pubmed ID:
12967501
Pubmed Central ID:
PMC3020613
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:c7d50f7af35a88b48a9caa61171f5d6b7f767c432d5349a3210b7811e1592f75
Download URL:
https://stacks.cdc.gov/view/cdc/14258/cdc_14258_DS1.pdf
File Type:

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