Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09

Daulagala, Pavithra; Cheng, Samuel M.S.; Chin, Alex; Luk, Leo L.H.; Leung, Kathy; Wu, Joseph T.; Poon, Leo L.M.; Peiris, Malik; Yen, Hui-Ling

doi:10.3201/eid3001.230756

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Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09

1 2024
By Daulagala, Pavithra ; Cheng, Samuel M.S. ; Chin, Alex ; ...
http://dx.doi.org/10.3201/eid3001.230756
Source: Emerg Infect Dis. 2024; 30(1):168-171

[PDF-843.02 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Daulagala, Pavithra ; Cheng, Samuel M.S. ; Chin, Alex ; Luk, Leo L.H. ; Leung, Kathy ; ... More +

Daulagala, Pavithra ; Cheng, Samuel M.S. ; Chin, Alex ; Luk, Leo L.H. ; Leung, Kathy ; Wu, Joseph T. ; Poon, Leo L.M. ; Peiris, Malik ; Yen, Hui-Ling Less -
Description:

We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.
Subjects:

[+]

Adult Animals Antibodies, Viral Humans Influenza, Human Influenza A Virus, H1N1 Subtype Influenza A Virus, H5N1 Subtype Influenza In Birds Influenza Vaccines Neuraminidase
Keywords:

[+]

Clade 2.3.4.4.b Cross-reactive Antibody Response Influenza Influenza A(H1N1)pdm09 Influenza A(H5N1) Neuraminidase Inhibition Antibody Pandemic Risk Assessment Respiratory Infections Viruses
Source:

Emerg Infect Dis. 2024; 30(1):168-171
Pubmed ID:

38147510
Pubmed Central ID:

PMC10756388
Document Type:

Journal Article
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

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urn:sha256:56960c0c8658de03619f3b2eda8a3b52723eb6857a056b7f80b8dbbae649bde4
Download URL:

https://stacks.cdc.gov/view/cdc/140570/cdc_140570_DS1.pdf
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	23-0756-F.jpg	jpeg
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