Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Olsen, Christopher W. ; Brammer, Lynnette ; Easterday, Bernard C. ; Arden, Nancy ; Belay, Ermias ; Baker, Inger ; Cox, Nancy J.
• Description:
  We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers > or = 40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn > or = 4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses.
• Subjects:
  Adolescent Adult Animals Antibodies, Viral Carrier State Child H1 Hemagglutination-inhibition Hemagglutination Inhibition Tests Humans Influenza Influenza, Human Influenza A Virus Middle Aged Questionnaires Research Serologic Tests Seroprevalence Swine Swine Diseases Zoonoses Zoonosis

  More +
• Source:
  Emerg Infect Dis. 8(8):814-819.
• Document Type:
  Journal Article
• Volume:
  8
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:c6b0cafc0870da05cd8246ca74eaaaf1b0d613c9ee23585728a429c474cfcf26
• Download URL:
  https://stacks.cdc.gov/view/cdc/13876/cdc_13876_DS1.pdf
• File Type:
  [PDF - 245.61 KB ]