Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Foppa, Ivo M. ; Krause, Peter J. ; Spielman, Andrew ; Goethert, Heidi ; Gern, Lise ; ... More +
Foppa, Ivo M. ; Krause, Peter J. ; Spielman, Andrew ; Goethert, Heidi ; Gern, Lise ; Brand, Brigit ; Telford, Sam R. Less -
Description:
We evaluated human risk for infection with Babesia microti at a site in eastern Switzerland where several B. microti-infected nymphal Ixodes ricinus ticks had been found. DNA from pooled nymphal ticks amplified by polymerase chain reaction was highly homologous to published B. microti sequences. More ticks carried babesial infection in the lower portion of the rectangular 0.7-ha grid than in the upper (11% vs. 0.8%). In addition, we measured seroprevalence of immunoglobulin (Ig) G antibodies against B. microti antigen in nearby residents. Serum from 1.5% of the 396 human residents of the region reacted to B. microti antigen (>1:64), as determined by indirect immunofluorescence assay (IgG). These observations constitute the first report demonstrating B. microti in a human-biting vector, associated with evidence of human exposure to this agent in a European site.
Subject:
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Animals
Antibodies, Protozoan
Antigens, Protozoan
Arthropod Vectors
Babesia
Babesiosis
DNA, Protozoan
Humans
Ixodes
Molecular Sequence Data
Phylogeny
Polymerase Chain Reaction
Risk Factors
Serologic Tests
Species Specificity

Source:
Emerg Infect Dis. 8(7):722-726.
Document Type:
Journal Article
Place as Subject:
Europe ; Switzerland
Europe ; Switzerland Less -
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:8974961f8eec6dd237efe29e0cec79199455396bb447fcb772a390eb2fe504ae
File Type:

Supporting Files

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