Treatment of Mpox with Suspected Tecovirimat Resistance in Immunocompromised Patient, United States, 2022

Contag, Caitlin A.; Mische, Leah; Fong, Isabel; Karan, Abraar; Vaidya, Akanksha; McCormick, David W.; Bower, William; Hacker, Jill K.; Johnson, Kelly; SanJuan, Perla; Crebbin, Linda; Temmins, Caroline; Sahni, Harleen; Bogler, Yael; Cooper, Joseph D.; Narasimhan, Supriya

doi:10.3201/eid2912.230849

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Treatment of Mpox with Suspected Tecovirimat Resistance in Immunocompromised Patient, United States, 2022

12 2023
By Contag, Caitlin A. ; Mische, Leah ; Fong, Isabel ; ...
http://dx.doi.org/10.3201/eid2912.230849
Source: Emerg Infect Dis. 2023; 29(12):2520-2523

[PDF-4.53 MB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Contag, Caitlin A. ; Mische, Leah ; Fong, Isabel ; Karan, Abraar ; Vaidya, Akanksha ; ... More +

Contag, Caitlin A. ; Mische, Leah ; Fong, Isabel ; Karan, Abraar ; Vaidya, Akanksha ; McCormick, David W. ; Bower, William ; Hacker, Jill K. ; Johnson, Kelly ; SanJuan, Perla ; Crebbin, Linda ; Temmins, Caroline ; Sahni, Harleen ; Bogler, Yael ; Cooper, Joseph D. ; Narasimhan, Supriya Less -
Description:

Reports of tecovirimat-resistant mpox have emerged after widespread use of antiviral therapy during the 2022 mpox outbreak. Optimal management of patients with persistent infection with or without suspected resistance is yet to be established. We report a successfully treated case of severe mpox in California, USA, that had suspected tecovirimat resistance.
Subjects:

[+]

Dispatch Expedited Treatment Of Mpox With Suspected Tecovirimat Resistance In Immunocompromised Patient, United States, 2022
Keywords:

[+]

Antiviral Drug Benzamides Disease Outbreaks Drug Resistance HIV/AIDS Human Immunodeficiency Virus Humans Immunocompromised Host Monkeypox Monkeypox Virus Mpox Mpox (monkeypox) MPX MPXV Severe Infection Tecovirimat Tecovirimat Resistance United States Viruses
Source:

Emerg Infect Dis. 2023; 29(12):2520-2523
Pubmed ID:

37856215
Pubmed Central ID:

PMC10683816
Document Type:

Journal Article
Funding:

U01 CK000539/CK/NCEZID CDC HHSUnited States/ ; U01CK000539/ACL/ACL HHSUnited States/

U01 CK000539/CK/NCEZID CDC HHSUnited States/ ; U01CK000539/ACL/ACL HHSUnited States/ Less -
Volume:

29
Issue:

12
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:2f0743ea7f75826168d89d50119efae467295f71d10facfd636d20dd8881d724
Download URL:

https://stacks.cdc.gov/view/cdc/138531/cdc_138531_DS1.pdf
File Type:

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