Risk Factors for Enteric Pathogen Exposure among Children in Black Belt Region of Alabama, USA

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Capone, Drew ; Bakare, Toheedat ; Barker, Troy ; Chatham, Amy Hutson ; Clark, Ryan ; Copperthwaite, Lauren ; Flemister, Abeoseh ; Geason, Riley ; Hoos, Emery ; Kim, Elizabeth ; Manoj, Alka ; Pomper, Sam ; Samodal, Christina ; Smith, Simrill ; Poole, Claudette ; Brown, Joe
• Description:
  We collected stool from school-age children from 352 households living in the Black Belt region of Alabama, USA, where sanitation infrastructure is lacking. We used quantitative reverse transcription PCR to measure key pathogens in stool that may be associated with water and sanitation, as an indicator of exposure. We detected genes associated with |1 targets in 26% of specimens, most frequently | (6.6%), atypical enteropathogenic | (6.1%), and enteroaggregative | (3.9%). We used generalized estimating equations to assess reported risk factors for detecting |1 pathogen in stool. We found no association between lack of sanitation and pathogen detection (adjusted risk ratio 0.95 [95% CI 0.55–1.7]) compared with specimens from children served by sewerage. However, we did observe an increased risk for pathogen detection among children living in homes with well water (adjusted risk ratio 1.7 [95% CI 1.1–2.5]) over those reporting water utility service.
• Subjects:
  Research Risk Factors For Enteric Pathogen Exposure Among Children In Black Belt Region Of Alabama, USA
• Keywords:
  Alabama Black Belt Child Enteric Infections Enteric Pathogens Humans Poverty Risk Factors Sanitation Straight Pipe United States Well Water

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• Source:
  Emerg Infect Dis. 2023; 29(12):2433-2441
• Pubmed ID:
  37987604
• Pubmed Central ID:
  PMC10683812
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:914dde0d3fe54b7cc9e7a186afe626f9960982f116dc09a39fb4f7d06efae9f4
• Download URL:
  https://stacks.cdc.gov/view/cdc/138528/cdc_138528_DS1.pdf
• File Type:
  [PDF - 1.55 MB ]