Invasive Nocardia Infections across Distinct Geographic Regions, United States

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Gupta, Simran ; Grant, Leah M. ; Powers, Harry R. ; Kimes, Kathryn E. ; Hamdi, Ahmed ; Butterfield, Richard J. ; Gea-Banacloche, Juan ; Vijayvargiya, Prakhar ; Hata, D. Jane ; Meza Villegas, Diana M. ; Dumitrascu, Adrian C. ; Harris, Dana M. ; Chirila, Razvan M. ; Zhang, Nan ; Razonable, Raymund R. ; Kusne, Shimon ; Alvarez, Salvador ; Vikram, Holenarasipur R.
• Description:
  We reviewed invasive | infections in 3 noncontiguous geographic areas in the United States during 2011–2018. Among 268 patients with invasive nocardiosis, 48.2% were from Minnesota, 32.4% from Arizona, and 19.4% from Florida. Predominant species were | complex in Minnesota (33.4%), | in Arizona (41.4%), and | in Florida (17.3%). Transplant recipients accounted for 82/268 (30.6%) patients overall: 14 (10.9%) in Minnesota, 35 (40.2%) in Arizona, and 33 (63.5%) in Florida. Manifestations included isolated pulmonary nocardiosis among 73.2% of transplant and 84.4% of non–transplant patients and central nervous system involvement among 12.2% of transplant and 3.2% of non–transplant patients. | (20.7%) and | (19.5%) were the most common isolates among transplant recipients and | (38.0%), | (23.7%), and | (16.1%) among non–transplant patients. Overall antimicrobial susceptibilities were similar across the 3 study sites.
• Subjects:
  Invasive Nocardia Infections Across Distinct Geographic Regions, United States Synopsis
• Keywords:
  Anti-Bacterial Agents Bacteria Disseminated Environmental Pathogens Humans Invasive Infections Nocardia Nocardia Infections Nocardiosis Transplant Transplantation-associated Infections United States

  More +
• Source:
  Emerg Infect Dis. 2023; 29(12):2417-2425
• Pubmed ID:
  37987603
• Pubmed Central ID:
  PMC10683819
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:62e068c251d72e57e652aa8bb3d77893ecff0bfdfaa354e3ae14522fe6448bc0
• Download URL:
  https://stacks.cdc.gov/view/cdc/138521/cdc_138521_DS1.pdf
• File Type:
  [PDF - 1.33 MB ]