Parachlamydiaceae: Potential Emerging Pathogens

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Greub, Gilbert ; Raoult, Didier
• Description:
  Parachlamydiaceae, which naturally infect amoebae, form a sister taxon to the Chlamydiaceae on the basis of the Chlamydia-like cycle of replication and 80% to 90% homology of ribosomal RNA genes. Because intra-amoebal growth could increase the virulence of some intracellular bacteria, Parachlamydiaceae may be pathogenic. Arguments supporting a pathogenic role are that Chlamydia pneumoniae, a well-recognized agent of pneumonia, was shown to infect free-living amoebae and that another member of the Chlamydiales, Simkania negevensis, which has 88% homology with Parachlamydia acanthamoebae, has caused pneumonia in adults and acute bronchiolitis in infants. The recent identification of a 16S rRNA gene sequence of a Parachlamydiaceae from bronchoalveolar lavage is additional evidence supporting potential for pathogenicity.
• Subjects:
  • Synopsis
  • Parachlamydiaceae
  • pathogenicity
  • free-living amoebae
  • Acanthamoeba
  • Animals
  • Chlamydiales
  • Community-Acquired Infections
  • Humans
  • Phylogeny
  More +
• Source:
  Emerg Infect Dis. 8(6):626-630.
• Document Type:
  Journal Article
• Volume:
  8
• Issue:
  6
• Download URL:
  https://stacks.cdc.gov/view/cdc/13786/cdc_13786_DS1.pdf
• File Type:
  [PDF - 690.33 KB]
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:6b654b81f0d2e6a67bfa911804b290a0a3fbfb854b459eece08f511f5bfe8256