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INTERACTION PROFILE FOR MIXTURES OF INSECTICIDES: PYRETHROIDS, ORGANOPHOSPHORUS COMPOUNDS, AND CARBAMATES
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July 2023
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[PDF-1.73 MB]
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Description:"The purpose of an Interaction Profile is to evaluate data on the toxicology of the “whole” priority mixture (if available) and on the joint toxic action of the chemicals in the mixture in order to recommend approaches for the exposure-based assessment of the potential hazard to public health. Joint toxic action includes additivity and interactions. A weight-of-evidence approach is commonly used in these documents to evaluate the influence of interactions in the overall toxicity of the mixture. The weight-ofevidence evaluations are qualitative in nature, although ATSDR recognizes that observations of toxicological interactions depend greatly on exposure doses and that some interactions appear to have thresholds. Thus, the interactions are evaluated in a qualitative manner to provide a sense of what influence the interactions may have when they do occur."
ip15.pdf
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Pages in Document:114 numbered pages in various paginations
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