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Prevention and control of meningococcal disease : recommendations of the Advisory Committee on Immunization Practices (ACIP)
  • Published Date:
    March 22, 2013
  • Status:
    current
Filetype[PDF - 25.30 MB]


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Prevention and control of meningococcal disease : recommendations of the Advisory Committee on Immunization Practices (ACIP)
Details:
  • Corporate Authors:
    United States. Advisory Committee on Immunization Practices. ; Centers for Disease Control and Prevention (U.S.) ; National Center for Immunization and Respiratory Diseases (U.S.), Division of Bacterial Diseases.
  • Series:
    Morbidity and mortality weekly report. Recommendations and reports, v. 62, no. RR-2
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 62, no. RR-2
  • Document Type:
  • Description:
    Introduction -- Methods -- Background -- Meningococcal vaccines -- Postlicensure safety surveillance for meningococcal conjugate vaccines -- Cost-effectiveness analyses -- Rationale for recommendations for use of meningococcal -- Vaccines -- Recommendations for use of meningococcal vaccines -- Future meningococcal vaccines, areas for research, and public education -- References -- Appendix A. Antimicrobial chemoprophylaxis -- Appendix B. Evaluation and management of suspected outbreaks of meningococcal disease

    Meningococcal disease describes the spectrum of infections caused by Neisseria meningiditis, including meningitdis, bacteremia, and bacteremic pneumonia. Two quadrivalent meningococcal polysaccharide-protein conjugate vaccines that provide protection against meningococcal serogroups A, C, W, and Y (MenACWY-D [Menactra, manufactured by Sanofi Pasteur, Inc., Swiftwater, Pennsylvania] and MenACWY-CRM [Menveo, manufactured by Novartis Vaccines, Cambridge, Massachusetts]) are licensed in the United States for use among persons aged 2 through 55 years. MenACWY-D also is licensed for use among infants and toddlers aged 9 through 23 months. Quadrivalent meningococcal polysaccharide vaccine (MPSV4 [Menommune, manufactured by sanofi pasteur, Inc., Swiftwater, Pennsylvania]) is the only vaccine licensed for use among persons aged ?56 years. A bivalent meningococcal polysaccharide protein conjugate vaccine that provides protection against meningococcal serogroups C and Y along with Haemophilus influenzae type b (Hib) (Hib-MenCY-TT [MenHibrix, manufactured by GlaxoSmithKline Biologicals, Rixensart, Belgium]) is licensed for use in children aged 6 weeks through 18 months. This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of meningococcal disease in the United States, specifically the changes in the recommendations published since 2005 (CDC. Prevention and control of meningococcal disease: recommendations of the Advisory Committee on Immunization Practices [ACIP]. MMWR 2005;54[No. RR-7]). As a comprehensive summary of previously published recommendations, this report does not contain any new recommendations; it is intended for use by clinicians as a resource. ACIP recommends routine vaccination with a quadrivalent meningococcal conjugate vaccine (MenACWY) for adolescents aged 11 or 12 years, with a booster dose at age 16 years. ACIP also recommends routine vaccination for persons at increased risk for meningococcal disease (i.e., persons who have persistent complement component deficiencies, persons who have anatomic or functional asplenia, microbiologists who routinely are exposed to isolates of N. meningitidis, military recruits, and persons who travel to or reside in areas in which meningococcal disease is hyperendemic or epidemic). Guidelines for antimicrobial chemoprophylaxis and for evaluation and management of suspected outbreaks of meningococcal disease also are provided.

  • Supporting Files:
    No Additional Files
  1. Updated recommendation from the Advisory Committee on Immunization Practices (ACIP) for revaccination of persons at prolonged increased risk for meningococcal disease.
  2. Meningococcal disease and college students. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
  3. Prevention and control of meningococcal disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP).
  4. Updated Recommendations for Use of Meningococcal Conjugate Vaccines -- Advisory Committee on Immunization Practices (ACIP), 2010
  5. Control and Prevention of Serogroup C Meningococcal Disease: Evaluation and Management of Suspected Outbreaks: Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1997; 46 (No. RR-05).
  6. Control and prevention of meningococcal disease: recommendations of the Advisory Committee on Immunization Practices (ACIP).
  7. Revised recommendations of the Advisory Committee on Immunization Practices to Vaccinate all Persons Aged 11-18 Years with Meningococcal Conjugate Vaccine.
  8. Recommendation of the Advisory Committee on Immunization Practices (ACIP) for Use of Quadrivalent Meningococcal Conjugate Vaccine (MenACWY-D) Among Children Aged 9 Through 23 Months at Increased Risk for Invasive Meningococcal Disease. MMWR 60 (40): 1391-1392.
  9. Licensure of a meningococcal conjugate vaccine (Menveo) and guidance for use - Advisory Committee on Immunization Practices (ACIP), 2010.
  10. Prevention and control of meningococcal disease : recommendations of the Advisory Committee on Immunization Practices (ACIP).
  11. Licensure of a Meningococcal Conjugate Vaccine for Children Aged 2 Through 10 Years and Updated Booster Dose Guidance for Adolescents and Other Persons at Increased Risk for Meningococcal Disease - Advisory Committee on Immunization Practices (ACIP), 2011. MMWR 2011; 60 (30):1018-1019.
  12. Report from the Advisory Committee on Immunization Practices (ACIP): Decision Not to Recommend Routine Vaccination of All Children Aged 2-10 Years with Quadrivalent Meningococcal Conjugate Vaccine (MCV4)