Details:

Alternative Title:
Prev Chronic Dis
Personal Author:
Lichtenstein, Kenneth A. ; Armon, Carl ; Buchacz, Kate ; Chmiel, Joan S. ; Buckner, Kern ; ... More +
Lichtenstein, Kenneth A. ; Armon, Carl ; Buchacz, Kate ; Chmiel, Joan S. ; Buckner, Kern ; Tedaldi, Ellen ; Wood, Kathleen ; Holmberg, Scott D. ; Brooks, John T. Less -
Corporate Authors:
HOPS Investigators
Description:
Introduction

Compliance with National Cholesterol Education Program Adult Treatment Panel III (NCEP) guidelines has been shown to significantly reduce incident cardiovascular events. We investigated physicians’ compliance with NCEP guidelines to reduce cardiovascular disease (CVD) risk in a population infected with HIV.

Methods

We analyzed HIV Outpatient Study (HOPS) data, following eligible patients from January 1, 2002, or first HOPS visit thereafter to calculate 10-year cardiovascular risk (10yCVR), until September 30, 2009, death, or last office visit. We categorized participants into four 10yCVR strata, according to guidelines determined by NCEP, the Infectious Disease Society of America, and the Adult AIDS Clinical Trials Group. We calculated percentages of patients treated for dyslipidemia and hypertension, calculated percentages of patients who achieved recommended goals, and categorized them by 10yCVR stratum.

Results

Of 2,005 patients analyzed, 33.7% had fewer than 2 CVD risk factors. For patients who had 2 or more risk factors, 10yCVR was less than 10% for 28.2%, 10% to 20% for 18.2%, and higher than 20% for 20.0% of patients. Of patients eligible for treatment, 81% to 87% were treated for elevated low-density lipoprotein cholesterol/non–high-density lipoprotein cholesterol (LDL-C/non–HDL-C), 2% to 11% were treated for low HDL-C, 56% to 91% were treated for high triglycerides, and 46% to 69% were treated for hypertension. Patients in higher 10yCVR categories were less likely to meet treatment goals than patients in lower 10yCVR categories.

Conclusion

At least one-fifth of contemporary HOPS patients have a 10yCVR higher than 20%, yet a large percentage of at-risk patients who were eligible for pharmacologic treatment did not receive recommended interventions and did not reach recommended treatment goals. Opportunities exist for CVD prevention in the HIV-infected population.


Subject:
[+]
Adult
Cardiovascular Diseases
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Cohort Studies
Dyslipidemias
Fasting
Female
Follow-Up Studies
Guideline Adherence
HIV Infections
Humans
Hypertension
Life Style
Male
Middle Aged
Office Visits
Outpatients
Risk Assessment

Source:
Prev Chronic Dis. 10.
Document Type:
Journal Article
Place as Subject:
United States
Collection(s):
Preventing Chronic Disease
Main Document Checksum:
[+]
urn:sha256:608fb84738a7395ef43ce09d2e78369908fc64b40bf32712babb4b42e556f46c
File Type:

Supporting Files

• 	license.txt	txt
  	PCD-10-E10.nxml	txt
  	PCD-10-E10s01.gif	gif
  	PCD-10-E10s01.jpg	jpeg
  	PCD-10-E10s02.gif	gif
  	PCD-10-E10s02.jpg	jpeg
  	PCD-10-E10s03.gif	gif
  	PCD-10-E10s03.jpg	jpeg

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