Response to Vaccine-Derived Polioviruses Detected through Environmental Surveillance, Guatemala, 2019

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Rodríguez, Rodrigo ; Juárez, Elisa ; Estívariz, Concepción F. ; Cajas, Coralia ; Rey-Benito, Gloria ; Amézquita, María Olga Bautista ; Miles, Stacey Jeffries ; Orantes, Oscar ; Freire, María Cecilia ; Chévez, Ana-Elena ; Signor, Leticia Castillo ; Sayyad, Leanna ; Jarquin, Claudia ; Cain, Emilia ; Villalobos Rodríguez, Andrea Patricia ; Mendoza, Linda ; Ovando, Carlos A. ; Mayorga, Haroldo de Jesús Barillas ; Gaitán, Ericka ; Paredes, Antonio ; Belgasmi-Allen, Hanen ; Gobern, Lorena ; Rondy, Marc
• Description:
  Guatemala implemented wastewater-based poliovirus surveillance in 2018, and three genetically unrelated vaccine-derived polioviruses (VDPVs) were detected in 2019. The Ministry of Health (MoH) response included event investigation through institutional and community retrospective case searches for acute flaccid paralysis (AFP) during 2018-2020 and a bivalent oral polio/measles, mumps, and rubella vaccination campaign in September 2019. This response was reviewed by an international expert team in July 2021. During the campaign, 93% of children 6 months <7 years of age received a polio-containing vaccine dose. No AFP cases were detected in the community search; institutional retrospective searches found 37% of unreported AFP cases in 2018‒2020. No additional VDPV was isolated from wastewater. No evidence of circulating VDPV was found; the 3 isolated VDPVs were classified as ambiguous VDPVs by the international team of experts. These detections highlight risk for poliomyelitis reemergence in countries with low polio vaccine coverage.
• Subjects:
  Child Environmental Monitoring Guatemala Humans Polio Poliomyelitis Poliovirus Poliovirus Vaccine, Oral Response To Vaccine-Derived Polioviruses Detected Through Environmental Surveillance, Guatemala, 2019 Retrospective Studies Synopsis Vaccination Viruses Wastewater

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• Source:
  Emerg Infect Dis. 2023; 29(8):1524-1530
• Pubmed ID:
  37486156
• Pubmed Central ID:
  PMC10370855
• Document Type:
  Journal Article
• Volume:
  29
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:50e373814bf916af06e1654e573211af33d4995477aa6a1b9f3ece803db6b060
• Download URL:
  https://stacks.cdc.gov/view/cdc/132620/cdc_132620_DS1.pdf
• File Type:
  [PDF - 921.57 KB ]