Healthcare-Associated Infections Caused by Mycolicibacterium neoaurum

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Shapiro, Kate ; Cross, Shane J. ; Morton, Ted H. ; Inaba, Hiroto ; Holland, Ashley ; Fasipe, Francisca R. ; Adderson, Elisabeth E.
• Description:
  Mycolicibacterium neoaurum is a rapidly growing mycobacterium and an emerging cause of human infections. M. neoaurum infections are uncommon but likely underreported, and our understanding of the disease spectrum and optimum management is incomplete. We summarize demographic and clinical characteristics of a case of catheter-related M. neoaurum bacteremia in a child with leukemia and those of 36 previously reported episodes of M. neoaurum infection. Most infections occurred in young to middle-aged adults with serious underlying medical conditions and commonly involved medical devices. Overall, infections were not associated with severe illness or death. In contrast to other mycobacteria species, M. neoaurum was generally susceptible to multiple antimicrobial drugs and responded promptly to treatment, and infections were associated with good outcomes after relatively short therapy duration and device removal. Delays in identification and susceptibility testing were common. We recommend using combination antimicrobial drug therapy and removal of infected devices to eradicate infection.
• Subjects:
  Child Cross Infection Delivery Of Health Care Humans Middle Aged Mycobacteriaceae Mycobacterium Mycobacterium Infections Young Adult
• Source:
  Emerg Infect Dis. 2023; 29(8):1516-1523
• Pubmed ID:
  37486155
• Pubmed Central ID:
  PMC10370869
• Document Type:
  Journal Article
• Place as Subject:
  Australia ; Canada ; China ; Japan ; Italy ; Republic of Korea ; Spain ; United Kingdom ; United States
• Volume:
  29
• Issue:
  8
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:4b404bdbd53c87a3b87d3d25d0b8361e192acf15863edd83d6bc4c3e282d3a42
• Download URL:
  https://stacks.cdc.gov/view/cdc/132610/cdc_132610_DS1.pdf
• File Type:
  [PDF - 1.07 MB ]