PrEP; a new tool for HIV prevention
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Filetype[PDF-162.24 KB]



  • Alternative Title:
    CDC interim guidance on HIV pre-exposure prophylaxis;Pre-exposure prophylaxis : a new tool for HIV prevention;
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  • Description:
    Pre-exposure prophylaxis, or PrEP, is a new HIV prevention method in which people who do not have HIV infection take a pill daily to reduce their risk of becoming infected. The pill contains medicines that prevent HIV from making new virus as it enters the body. In this way PrEP medicines can help keep the virus from establishing a permanent infection. Providing a preventive medication before exposure to a germ or virus is not a new practice and has been used to prevent other diseases. For example, when individuals travel to an area where malaria is common, they are advised to take malaria medication before and during travel to prevent getting infected if bitten by a mosquito carrying the malaria parasite. However, the use of medication to prevent HIV infection has only recently been evaluated. When used consistently, PrEP has been shown to reduce the risk of HIV infection among adults at very high risk for HIV infection through sex, including men who have sex with men and heterosexually-active men and women. CDC is also evaluating PrEP's effectiveness in preventing HIV infection among individuals exposed to HIV through injecting drugs, but those results are not yet available. For some individuals at very high risk for sexual exposure to HIV, PrEP may represent a much-needed additional prevention method - but it will not be right for everyone. PrEP is an intensive approach that requires strict adherence to daily medication and regular HIV testing. It is not intended to be used in isolation, but rather in combination with other HIV prevention methods. If it is used effectively and by persons at very high risk, PrEP may play a role in helping to reduce the number of new HIV infections in the United States.
  • Content Notes:
    August 2012.

    Contains: CDC interim guidance on HIV pre-exposure prophylaxis.

    Available via the World Wide Web as an Acrobat .pdf fiel (162.24 KB, 4 p.).

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