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Poliovirus vaccination options for achieving eradication and securing the endgame✩
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6 2013
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Source: Curr Opin Virol. 3(3):309-315
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Alternative Title:Curr Opin Virol
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Description:In 1988, the World Health Assembly resolved to globally eradicate poliomyelitis. As part of a four-pronged strategy with establishment of enhanced surveillance, institution of national immunization days, strengthening routine immunization, and carrying-out mopping-up activities, oral poliovirus vaccine (OPV) was selected as the vaccine-of-choice for eradication. Massive OPV use decreased the number of polio-endemic countries from >125 countries in 1988 to only 3 in 2012 and led to a >99.9% decrease in polio incidence in the corresponding period. In this communication, we will discuss polio vaccination options to accelerate eradication, to mitigate the risks during the planned withdrawal of type 2 OPV, and to secure eradication for future generations.
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Pubmed ID:23759252
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Pubmed Central ID:PMC10395005
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Volume:3
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Issue:3
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