Emerging glaucoma treatments: are we seeing an improvement in adherence?

Details

• Alternative Title:
  Expert Rev Ophthalmol
• Personal Author:
  Droste, Andrew P ; Newman-Casey, Paula Anne
• Description:
  Introduction:
  
  Non-adherence to glaucoma medication and poor follow-up is a global health concern.
  
  Areas covered:
  
  Glaucoma remains one of the largest causes of irreversible blindness worldwide. Traditional treatment guidelines suggest topical eye drop medication as first line therapy followed by addition of supplementary medications before proceeding to more invasive glaucoma surgeries. Unfortunately, poor glaucoma self-management remains high, leading to disease progression and blindness. Recent advancements in the field of pharmacotherapies, surgeries, and behavioral approaches have taken aim at increasing support for glaucoma self-management. We review the current and emerging approaches towards glaucoma management, with the exception of bleb-based surgical approaches, to investigate if they have had an impact on adherence. Literature searches were conducted via MEDLINE (PubMed), Embase (Elsevier), Cochrane Library (Wiley), and Preprints from January 1st, 2018, to January 26th, 2023.
  
  Expert opinion:
  
  The ability to offer patients a multitude of choices enables patients to tailor their glaucoma treatment to their values and lifestyle. Offering personalized patient education and coaching to support chronic glaucoma self-management would better enable patient engagement in whichever treatment path is chosen. Currently, literature regarding the impact of these new advancements on treatment engagement is lacking; this field is ripe for additional intervention and assessment.
  
  
• Keywords:
  Glaucoma Hydrus Intracameral Implants IStent Latanoprostene Bunod Medication Adherence Micro Invasive Glaucoma Surgery (MIGS) Nanotechnology
• Source:
  Expert Rev Ophthalmol. 18(2):101-111
• Pubmed ID:
  37520660
• Pubmed Central ID:
  PMC10373909
• Document Type:
  Journal Article
• Funding:
  R01 EB032328/EB/NIBIB NIH HHSUnited States/ ; R01 EY031337/EY/NEI NIH HHSUnited States/ ; U01 DP006442/DP/NCCDPHP CDC HHSUnited States/
• Volume:
  18
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:ab7c2db655c1d4b0e76827765628f9b5cb6d26edfabdf87e529350d3ef290c7b
• Download URL:
  https://stacks.cdc.gov/view/cdc/131539/cdc_131539_DS1.pdf
• File Type:
  [PDF - 120.11 KB ]